二甲基 4-甲基异邻苯二甲酸酯合成路线 （共 15 条）
反应条件
in tetrahydrofuran; methanol
参考文献
Merck and Co., Inc.
Patent: US5648368 A1, 1997 ;
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane Heating;
参考文献
Egbertson; Hartman; Gould; Bednar; Cook; Gaul; Holahan; Libby; Lynch Jr.; Lynch; Sitko; Stranieri; Vassallo
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 21 p. 2519 - 2524
反应条件
N-bromosuccinmide in tetrachloromethane
参考文献
Chen, Gang; Crawford, Jason; Skerlj, Renato
Patent: US2005/154201 A1, 2005 ;
反应条件
dibenzoyl peroxide in tetrachloromethane; chloroform
参考文献
Merck and Co., Inc.
Patent: US5646000 A1, 1997 ;
参考文献
Egbertson; Hartman; Gould; Bednar; Cook; Gaul; Holahan; Libby; Lynch Jr.; Lynch; Sitko; Stranieri; Vassallo
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 21 p. 2519 - 2524
反应条件
CO; carbon monoxide; triethylamine; palladium diacetate in methanol; dimethyl sulfoxide
参考文献
Merck and Co., Inc.
Patent: US5272158 A1, 1993 ;
反应条件
1: (i) CuSO4, Py, PhCN, (ii) aq. NaOH
2: CuSO4, Py
View Scheme
参考文献
Strauss,M.J. et al.
Journal of the American Chemical Society, 1968 , vol. 90, # 13 p. 3473 - 3478
反应条件
1: water; sodium hydroxide / diethylene glycol / 120 h / |Reflux
2: sulfuric acid / 6 h / |Reflux
View Scheme
参考文献
Fischer, Stefan; Wentsch, Heike K.; Mayer-Wrangowski, Svenja C.; Zimmermann, Markus; Bauer, Silke M.; Storch, Kirsten; Niess, Raimund; Koeberle, Solveigh C.; Gruetter, Christian; Boeckler, Frank M.; Rauh, Daniel; Laufer, Stefan A.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 1 p. 241 - 253
反应条件
1: aq. KMnO4
2: ion-exchange resin <H+ form>
View Scheme
参考文献
Fissekis,J.D.; Sweet,F.
Journal of Organic Chemistry, 1973 , vol. 38, # 11 p. 1963 - 1970
反应条件
1: 1.) CH3MgBr, 2.) n-BuLi / 1.) 0 deg C, 2.) -65 deg C
2: 95 percent / HCl
View Scheme
参考文献
Egbertson; Hartman; Gould; Bednar; Cook; Gaul; Holahan; Libby; Lynch Jr.; Lynch; Sitko; Stranieri; Vassallo
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 21 p. 2519 - 2524
