3,6-二氢-4,6,6-三甲基-2H-吡喃-2-酮合成路线 （共 10 条）
反应条件
zinc in acetic acid T=40°C; 72 h;
参考文献
Bardili, Burkhart; Marschall-Weyerstahl, Helga; Weyerstahl, Peter
Liebigs Annalen der Chemie, 1985 , # 2 p. 275 - 300
反应条件
zinc in acetic acid T=40°C; 72 h;
参考文献
Bardili, Burkhart; Marschall-Weyerstahl, Helga; Weyerstahl, Peter
Liebigs Annalen der Chemie, 1985 , # 2 p. 275 - 300
反应条件
1: 1) NaH / 1) dioxane, 2) 12h, reflux 2: 1) 2N H2SO4, 2) hexamethyldisilazane / 1) acetone, 24h, 2) pyridine, 12h; 5h, 80 deg C 3: 97 percent / 2N H2SO4 / diethyl ether / 12 h 4: 20 percent / POCl3 / pyridine / 24 h / 70 °C 5: 58 percent / Zn / acetic acid / 72 h / 40 °C View Scheme
参考文献
Liebigs Annalen der Chemie, , # 2 p. 275 - 300
反应条件
1: 1) 2N H2SO4, 2) hexamethyldisilazane / 1) acetone, 24h, 2) pyridine, 12h; 5h, 80 deg C 2: 97 percent / 2N H2SO4 / diethyl ether / 12 h 3: 20 percent / POCl3 / pyridine / 24 h / 70 °C 4: 58 percent / Zn / acetic acid / 72 h / 40 °C View Scheme
参考文献
Liebigs Annalen der Chemie, , # 2 p. 275 - 300
反应条件
1: 20 percent / POCl3 / pyridine / 24 h / 70 °C 2: 58 percent / Zn / acetic acid / 72 h / 40 °C View Scheme
参考文献
Liebigs Annalen der Chemie, , # 2 p. 275 - 300
反应条件
1: 97 percent / 2N H2SO4 / diethyl ether / 12 h 2: 20 percent / POCl3 / pyridine / 24 h / 70 °C 3: 58 percent / Zn / acetic acid / 72 h / 40 °C View Scheme
参考文献
Liebigs Annalen der Chemie, , # 2 p. 275 - 300
反应条件
1: 1) 2N H2SO4, 2) hexamethyldisilazane / 1) acetone, 24h, 2) pyridine, 12h; 5h, 80 deg C 2: 97 percent / 2N H2SO4 / diethyl ether / 12 h 3: 20 percent / POCl3 / pyridine / 24 h / 70 °C 4: 58 percent / Zn / acetic acid / 72 h / 40 °C View Scheme
参考文献
Liebigs Annalen der Chemie, , # 2 p. 275 - 300
反应条件
boron fluoride ether
参考文献
Journal of the American Chemical Society, , vol. 71, p. 1346
反应条件
lithium diethylamide in tetrahydrofuran 1.) -70 deg C; 0 deg C, 1 h 20 min; 2.) -70 deg C, 1h; rt, 1 h;
参考文献
Aurell, Maria J.; Ceita, Luisa; Mestres, Ramon; Parra, Margarita; Tortajada, Amparo
Tetrahedron, 1995 , vol. 51, # 13 p. 3915 - 3928
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron, , vol. 49, # 27 p. 6089 - 6100
