(2-甲氧基苯基)(2-吡啶基)甲酮合成路线 （共 6 条）
反应条件
ferrous chloride tetrahydrate; oxygen; acetic acid in dimethyl sulfoxide T=100°C; 24 h;
参考文献
De Houwer, Johan; Abbaspour Tehrani, Kourosch; Maes, Bert U. W.
Angewandte Chemie - International Edition, 2012 , vol. 51, # 11 p. 2745 - 2748
反应条件
n-butyllithium in tetrahydrofuran; hexane T=10°C; Flow reactor;
参考文献
Liu, Binjie; Fan, Yong; Lv, Xiaoming; Liu, Xiaofeng; Yang, Yongtai; Jia, Yu
Organic Process Research and Development, 2013 , vol. 17, # 1 p. 133 - 137
反应条件
[Co(O2CCH3)2]*4H2O in 1,4-dioxane T=50°C; 4 h; chemoselective reaction;
参考文献
Karthikeyan; Alamsetti; Sekar
Organometallics, 2014 , vol. 33, # 7 p. 1665 - 1671
反应条件
1: 2-methoxybromobenzene With magnesium in tetrahydrofuran Inert atmosphere; 2: 2-pyridine carbonitrile in tetrahydrofuran T=0°C; Inert atmosphere; 3: With hydrogenchloride; water in diethyl ether 0.5 h; Inert atmosphere;
参考文献
Tao, Xiaoming; Li, Wanfang; Ma, Xin; Li, Xiaoming; Fan, Weizheng; Xie, Xiaomin; Ayad, Tahar; Ratovelomanana-Vidal, Virginie; Zhang, Zhaoguo
Journal of Organic Chemistry, 2012 , vol. 77, # 1 p. 612 - 616
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 - -50 °C / Inert atmosphere 1.2: 2 h / -50 °C / Inert atmosphere 1.3: Inert atmosphere 2.1: palladium (II) trifluoroacetate; caesium carbonate; tri-cyclo-hexyl-phosphine / o-xylene; toluene / 6 h / Inert atmosphere; Reflux 3.1: ferrous chloride tetrahydrate; oxygen; acetic acid / dimethyl sulfoxide / 24 h / 100 °C View Scheme
参考文献
De Houwer, Johan; Abbaspour Tehrani, Kourosch; Maes, Bert U. W.
Angewandte Chemie - International Edition, 2012 , vol. 51, # 11 p. 2745 - 2748
反应条件
1: palladium (II) trifluoroacetate; caesium carbonate; tri-cyclo-hexyl-phosphine / o-xylene; toluene / 6 h / Inert atmosphere; Reflux 2: ferrous chloride tetrahydrate; oxygen; acetic acid / dimethyl sulfoxide / 24 h / 100 °C View Scheme
参考文献
De Houwer, Johan; Abbaspour Tehrani, Kourosch; Maes, Bert U. W.
Angewandte Chemie - International Edition, 2012 , vol. 51, # 11 p. 2745 - 2748
