(5-甲基-吡啶-2-基)甲醇合成路线 （共 11 条）
参考文献
Yakugaku Zasshi, , vol. 79, p. 108
Chem.Abstr., , p. 10211
Helvetica Chimica Acta, , vol. 40, p. 2421,2424, 2425
反应条件
trifluoroacetic anhydride in N,N-dimethyl-formamide 16 h; Ambient temperature;
参考文献
Konno, Katsuhiro; Hashimoto, Kimiko; Shirahama, Haruhisa; Matsumoto, Takeshi
Heterocycles, 1986 , vol. 24, # 8 p. 2169 - 2172
反应条件
1: manganese (IV)-oxide; diethyl ether 2: AgNO3; aqueous NaOH; aqueous NH3 View Scheme
参考文献
Yakugaku Zasshi, , vol. 78, p. 661,665
Chem.Abstr., , p. 18399
反应条件
manganese(IV) oxide; diethyl ether
参考文献
Nakashima
Yakugaku Zasshi, 1958 , vol. 78, p. 661,665
Chem.Abstr., 1958 , p. 18399
反应条件
1: ethyl acetate; phosphoryl chloride 2: aqueous ethanol 3: aqueous hydrochloric acid View Scheme
参考文献
Arata; Achiwa
Yakugaku Zasshi, 1959 , vol. 79, p. 108
Chem.Abstr., 1959 , p. 10211
反应条件
thionyl chloride in chloroform
T=0°C;
参考文献
AMIRA PHARMACEUTICALS, INC.
Patent: US2009/291981 A1, 2009 ;
Location in patent: Page/Page column 42 ;
反应条件
in chloroform
T=0°C;
参考文献
RANBAXY LABORATORIES LIMITED
Patent: WO2004/52857 A1, 2004 ;
Location in patent: Page 61 ;
WO 2004/052857 A1
参考文献
Hoffmann-La Roche Inc.
Patent: US4182766 A1, 1980 ;
反应条件
1: With thionyl chloride in methanol
0.0833333 h; Heating / reflux;
2: With water; sodium hydrogencarbonate in diethyl ether
参考文献
Eisai RandD Management Co., Ltd.
Patent: US2007/105904 A1, 2007 ;
Location in patent: Page/Page column 88 ;
反应条件
1: ethyl acetate; phosphoryl chloride
2: aqueous ethanol
3: ethanolic HCl
View Scheme
参考文献
Arata; Achiwa
Yakugaku Zasshi, 1959 , vol. 79, p. 108
Chem.Abstr., 1959 , p. 10211
