4-苯甲酰基-4-苯基-1-(对甲苯基磺酰基)哌啶合成路线 （共 7 条）
反应条件
ammonium cerium(IV) nitrate; oxygen in acetonitrile T=20°C; 3 h;
参考文献
Chang, Meng-Yang; Wu, Tsun-Cheng; Lin, Chun-Yu; Hung, Ching-Yi
Tetrahedron Letters, 2006 , vol. 47, # 47 p. 8347 - 8350
反应条件
1: bromobenzene With magnesium in tetrahydrofuran 2: N-(p-tosyl)-4-phenyl-4-cyano-piperidine in toluene Inert atmosphereReflux;
参考文献
Efange, Simon M. N.; Khare, Anil B.; Von Hohenberg, Krystyna; MacH, Robert H.; Parsons, Stanley M.; Tu, Zhude
Journal of Medicinal Chemistry, 2010 , vol. 53, # 7 p. 2825 - 2835
反应条件
Celite; pyridinium chlorochromate in dichloromethane T=20°C; 6 h;
参考文献
Chang, Meng-Yang; Wu, Tsun-Cheng; Lin, Shiang-Tsern
Journal of the Chinese Chemical Society, 2008 , vol. 55, # 2 p. 468 - 473
反应条件
1: tetrahydrofuran / -78 °C 2: BF3*OEt2 / CH2Cl2 / 20 °C 3: 60 percent / ceric ammonium nitrate; O2 / acetonitrile / 3 h / 20 °C View Scheme
参考文献
Chang, Meng-Yang; Wu, Tsun-Cheng; Lin, Chun-Yu; Hung, Ching-Yi
Tetrahedron Letters, 2006 , vol. 47, # 47 p. 8347 - 8350
反应条件
1: BF3*OEt2 / CH2Cl2 / 20 °C 2: 60 percent / ceric ammonium nitrate; O2 / acetonitrile / 3 h / 20 °C View Scheme
参考文献
Chang, Meng-Yang; Wu, Tsun-Cheng; Lin, Chun-Yu; Hung, Ching-Yi
Tetrahedron Letters, 2006 , vol. 47, # 47 p. 8347 - 8350
反应条件
1: CH2Cl2 / 0 °C 2: tetrahydrofuran / -78 °C 3: BF3*OEt2 / CH2Cl2 / 20 °C 4: 60 percent / ceric ammonium nitrate; O2 / acetonitrile / 3 h / 20 °C View Scheme
参考文献
Chang, Meng-Yang; Wu, Tsun-Cheng; Lin, Chun-Yu; Hung, Ching-Yi
Tetrahedron Letters, 2006 , vol. 47, # 47 p. 8347 - 8350
反应条件
1: CH2Cl2 / 0 °C 2: tetrahydrofuran / -78 °C 3: BF3*OEt2 / CH2Cl2 / 20 °C 4: 60 percent / ceric ammonium nitrate; O2 / acetonitrile / 3 h / 20 °C View Scheme
参考文献
Chang, Meng-Yang; Wu, Tsun-Cheng; Lin, Chun-Yu; Hung, Ching-Yi
Tetrahedron Letters, 2006 , vol. 47, # 47 p. 8347 - 8350
