2-(2-溴乙基)苯甲醛合成路线 （共 32 条）
反应条件
bromine in dichloromethane T=38 - 40°C; 4 h; strong light source;
参考文献
TORRENT PHARMACEUTICALS LTD
Patent: WO2005/80333 A1, 2005 ;
Location in patent: Page/Page column 19-20 ;
反应条件
T=130°C; durch Erhitzen;
参考文献
Chemische Berichte, , vol. 89, p. 1254,1261
Chemische Berichte, , vol. 91, p. 1133,1138
反应条件
trimethylsilyl bromide; tetrabutylammomium bromide in toluene T=80°C; 4 h;
参考文献
Hashimoto, Takuya; Maeda, Yuko; Omote, Masato; Nakatsu, Hiroki; Maruoka, Keiji
Journal of the American Chemical Society, 2010 , vol. 132, # 12 p. 4076 - 4077
反应条件
1: Einleiten von HCl 2: CCl4; bromine / unter UV-Belichtung und Erhitzen des Rktprod. mit wss. HBr View Scheme
参考文献
Chemische Berichte, , vol. 89, p. 1254,1261
反应条件
1: trimethylsilyl trifluoromethanesulfonate / acetonitrile / 3 h / 0 °C / |Inert atmosphere 2: copper(ll) bromide / acetonitrile / |Reflux; |Inert atmosphere View Scheme
参考文献
Tetrahedron Letters, , vol. 54, # 30 p. 3962 - 3964
反应条件
water; hydrogen bromide
参考文献
Chemische Berichte, , vol. 90, p. 531,534
参考文献
Chemische Berichte, , vol. 90, p. 531,534
参考文献
Schmitz
Chemische Berichte, 1958 , vol. 91, p. 1133,1138
反应条件
1: 68 percent / benzene / 6 h / Heating 2: 88 percent / dimethylformamide / 24 h / 25 °C 3: 72 percent / hydrazine hydrate / ethanol / 6 h / Heating View Scheme
参考文献
Bunce, Richard A.; Peeples, Christopher J.; Jones, Paul B.
Journal of Organic Chemistry, 1992 , vol. 57, # 6 p. 1727 - 1733
反应条件
1: 80 percent / MeONa / methanol / 1 h / 0 °C 2: 53 percent / AcCl, FeCl3 / CH2Cl2 / 3 h / 0 - 5 °C 3: 95 percent / aq. NaH2PO2 / 10percent Pd-C / ethyl acetate / 0.58 h / Heating 4: 89 percent / ethanol; H2O / 24 h / Heating 5: 70 percent / aq. HCl / 2.5 h / Heating 6: 80 percent / pyridine / CH2Cl2 / 5 - 10 °C 7: H2O / 2 h / Heating View Scheme
参考文献
Hayler; Howie; Giles; Negus; Oxley; Walsgrove; Walsh; Dagger; Fortunak; Mastrocola
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 3 p. 875 - 882
