N(3)-甲基-2'-脱氧胞苷合成路线 （共 16 条）
反应条件
triethylamine in acetonitrile
T=55°C;
参考文献
Hofmann, Mechtild; Acedo, Montse; Fagan, Patricia; Wemmer, David; Eritja, Ramon; Diaz, Antonio R.
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 12 p. 1825 - 1828
反应条件
in ethanol
T=55°C; 168 h;
参考文献
Kraszewski; Delort; Teoule
Tetrahedron Letters, 1986 , vol. 27, # 7 p. 861 - 864
反应条件
in ethanol
T=55°C; 1 h;
参考文献
Kraszewski; Delort; Teoule
Tetrahedron Letters, 1986 , vol. 27, # 7 p. 861 - 864
反应条件
in water
T=65°C; 2 h;
参考文献
MacMillan, Andrew M.; Verdine, Gregory L.
Tetrahedron, 1991 , vol. 47, # 14/15 p. 2603 - 2616
反应条件
in N,N-dimethyl-formamide
T=70°C; 32 h;
参考文献
Hayashi, Masahiro; Yamauchi, Kiyoshi; Kinoshita, Masayoshi
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 1 p. 277 - 278
反应条件
in ethanol
1.5 h; Ambient temperature;
参考文献
Miah, Anwar; Reese, Colin B.; Song, Quanlai
Nucleosides and Nucleotides, 1997 , vol. 16, # 1-2 p. 53 - 65
反应条件
1: 58 percent / dimethyldioxirane / acetone; CH2Cl2 / 25 °C
2: 58 percent / 2N methanol. NH3 / 25 °C
View Scheme
参考文献
Saladino, Raffaele; Mincione, Enrico; Crestini, Claudia; Mezzetti, Maurizio
Tetrahedron, 1996 , vol. 52, # 19 p. 6759 - 6780
反应条件
1: 95 percent / NH3 / methanol / 2 h / Ambient temperature
2: 100 percent / H2O / 2 h / 65 °C
View Scheme
参考文献
MacMillan, Andrew M.; Verdine, Gregory L.
Tetrahedron, 1991 , vol. 47, # 14/15 p. 2603 - 2616
反应条件
1: 85 percent / triethylamine / CH2Cl2 / 2 h / Ambient temperature
2: 95 percent / NH3 / methanol / 2 h / Ambient temperature
3: 100 percent / H2O / 2 h / 65 °C
View Scheme
参考文献
MacMillan, Andrew M.; Verdine, Gregory L.
Tetrahedron, 1991 , vol. 47, # 14/15 p. 2603 - 2616
反应条件
in N,N-dimethyl-formamide
T=70°C; 32 h;
参考文献
Hayashi, Masahiro; Yamauchi, Kiyoshi; Kinoshita, Masayoshi
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 1 p. 277 - 278
