2-巯基-5-硝基苯并噁唑合成路线 （共 9 条）
反应条件
acetic acid in ethanol pH=5; 4.5 h; Reflux;
参考文献
Ongarora, Dennis S.B.; Gut, Jiri; Rosenthal, Philip J.; Masimirembwa, Collen M.; Chibale, Kelly
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 15 p. 5046 - 5050
反应条件
pyridine 1 h; Heating / reflux;
参考文献
ELI LILLY AND COMPANY
Patent: WO2006/66173 A2, 2006 ;
Location in patent: Page/Page column 47 ;
WO 2006/066173 A2
反应条件
1: With potassium carbonate in ethanol 2 h; Heating; 2: With dihydrogen peroxide in ethanol 1 h; Further stages.;
参考文献
Singh; Singh, Pallavi; Singh, Shweta
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2007 , vol. 46, # 10 p. 1666 - 1671
反应条件
Lawesson's reagent in xylene 5 h; Heating;
参考文献
Shridhar, D. R.; Jogibhukta, M.; Shanthan Rao, P.; Handa, Vijay K.
Synthesis, 1983 , # 11 p. 936 - 937
参考文献
Katz; Cohen
Journal of Organic Chemistry, 1954 , vol. 19, p. 758,762, 765
反应条件
hydrogenchloride; iron
参考文献
Katz; Cohen
Journal of Organic Chemistry, 1954 , vol. 19, p. 758,762, 765
反应条件
in N,N-dimethyl-formamide T=25°C; 4 h;
参考文献
Ongarora, Dennis S.B.; Gut, Jiri; Rosenthal, Philip J.; Masimirembwa, Collen M.; Chibale, Kelly
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 15 p. 5046 - 5050
反应条件
in diethyl ether T=10°C; 0.0333333 h;
参考文献
Zinner,H. et al.
Chemische Berichte, 1960 , vol. 93, p. 2035 - 2040
反应条件
phosphorus pentachloride; trichlorophosphate
T=100°C; 2.5 h;
参考文献
VASTOX PLC
Patent: WO2007/91106 A2, 2007 ;
Location in patent: Page/Page column 136 ;
