4-甲氧基苯基 异硫氰酸酯合成路线 （共 89 条）
反应条件
1: hydrazine / dichloromethane; water / 1 h
2: methanol / 5 h / Reflux
View Scheme
参考文献
Kang, Iou-Jiun; Wang, Li-Wen; Hsu, Tsu-An; Yueh, Andrew; Lee, Chung-Chi; Lee, Yen-Chun; Lee, Ching-Yin; Chao, Yu-Sheng; Shih, Shin-Ru; Chern, Jyh-Haur
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 7 p. 1948 - 1952
反应条件
in ethanol
8 h; Reflux;
参考文献
UNIVERSITA' DEGLI STUDI DI MILANO; UNIVERSITA' DEGLI STUDI DI PISA; ABBRACCHIO, Mariapia; EBERINI, Ivano; PARRAVICINI, Chiara; MARTINI, Claudia; TRINCAVELLI, Maria Letizia; DANIELE, Simona
Patent: WO2012/59869 A1, 2012 ;
Location in patent: Page/Page column 11-12 ;
WO 2012/059869 A1
参考文献
Kumelj; Tisler
Vestnik Slovensk.kem.DrustvaChem.Abstr., 1958 , vol. 5, p. 69,70,71;
Vestnik Slovensk.kem.DrustvaChem.Abstr., 1960 , p. 22426
反应条件
1: diethyl ether / und Behandeln des Reaktionsprodukts mit Schwefelsaeure
2: NaOH-solution / 20 °C
3: beim Schmelzen
View Scheme
参考文献
Worrall
Journal of the American Chemical Society, 1924 , vol. 46, p. 2836
反应条件
1: 82 percent / ethanol / 1 h / Heating
2: 76 percent / KOH / H2O / 2 h / Heating
View Scheme
参考文献
Kadry; Badawy; Hanna
Pharmazie, 1986 , vol. 41, # 8 p. 558 - 559
反应条件
in diethyl ether
Ambient temperature;
参考文献
Lieber,E. et al.
Journal of Organic Chemistry, 1963 , vol. 28, p. 257 - 258
反应条件
triethylamine in dichloromethane
T=20°C; 0.333333 h;
参考文献
Morgenstern, Olaf; Wanka, Heike; Roeser, Ilka; Steveling, Antje; Kuttler, Beate
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 5 p. 1071 - 1089
反应条件
potassium hydroxide in ethanol
4 h; Heating;
参考文献
Agrawal; Parmar; Dwivedi; Harbison
Journal of Pharmaceutical Sciences, 1977 , vol. 66, # 6 p. 887 - 889
反应条件
sulfur; triethylamine in N,N-dimethyl-formamide
参考文献
Demirayak, Seref; Ali, Faten Dali; Osman, Baland Sirvan; Tunali, Yagmur
Phosphorus, Sulfur and Silicon and the Related Elements, 2007 , vol. 182, # 8 p. 1793 - 1803
反应条件
tetrabutylammomium bromide; copper(I) bromide in dimethyl sulfoxide
T=40°C; 20 h;
参考文献
Liu, Jie; Zhang, Xiaobin; Yang, Jin; Wang, Lei
Applied Organometallic Chemistry, 2014 , vol. 28, # 3 p. 198 - 203
