8-(4-甲氧基苯基)-8-氧代辛酸合成路线 （共 12 条）
参考文献
Delorme, Daniel; Woo, Soon Hyung; Vaisburg, Arkadii
Patent: US2002/115826 A1, 2002 ;
反应条件
1.1: Zn; BrCH2CH2Br; Me3SiCl 1.2: LiCl; CuCN / tetrahydrofuran 1.3: tetrahydrofuran 2.1: aq. NaOH / tetrahydrofuran; methanol View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 1 p. 283 - 287
反应条件
1.1: 83 percent / NaI / acetone / Heating 2.1: Zn; (CH2)Br2; TMSCl / tetrahydrofuran / 16 h / 20 - 60 °C 2.2: CuCN; LiCl / tetrahydrofuran / 0.17 h / 0 °C 2.3: tetrahydrofuran / 3 h / 0 °C 3.1: 1 N aq. NaOH / tetrahydrofuran; methanol / 2 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 45, # 13 p. 2877 - 2885
反应条件
1.1: Zn; BrCH2CH2Br; Me3SiCl 1.2: LiCl; CuCN / tetrahydrofuran 1.3: tetrahydrofuran 2.1: aq. NaOH / tetrahydrofuran; methanol View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 1 p. 283 - 287
反应条件
1: SOCl2 2: AlCl3 View Scheme
参考文献
Journal of the Indian Chemical Society, , vol. 46, # 4 p. 351 - 357
反应条件
1: AlCl3 View Scheme
参考文献
Journal of the Indian Chemical Society, , vol. 46, # 4 p. 351 - 357
反应条件
aluminium trichloride; tetrachloroethane, 1,1,2,2-
反应条件
aluminium trichloride
参考文献
Journal of the Indian Chemical Society, , vol. 46, # 4 p. 351 - 357
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. 25, p. 56 - 68
反应条件
1: (i) NO, NO2, Ac2O, (ii) /BRN= 471382/, K2CO3 2: (saponification) View Scheme
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. 25, p. 56 - 68
