3-(2-氧代-环己基)-丙酸合成路线 （共 30 条）
反应条件
tetraphosphorus decasulfide in pyridine
T=114°C; 8 h;
参考文献
Klimenko, S. K.; Trushina, E. V.; Sorokin, N. N.; Yaskevich, N. N.; Bel'skii, V. K.
Russian Journal of Organic Chemistry, 1994 , vol. 30, # 3.1 p. 378 - 383
Zhurnal Organicheskoi Khimii, 1994 , vol. 30, # 3 p. 355 - 359
反应条件
water
1.) benzene, 80 deg C, 8 h, 2.) benzene; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Klimenko, S. K.; Trushina, E. V.; Sorokin, N. N.; Yaskevich, N. N.; Bel'skii, V. K.
Russian Journal of Organic Chemistry, 1994 , vol. 30, # 3.1 p. 378 - 383
Zhurnal Organicheskoi Khimii, 1994 , vol. 30, # 3 p. 355 - 359
参考文献
Schuscherina et al.
Zhurnal Obshchei Khimii, 1956 , vol. 26, p. 750,574; engl. Ausg. S. 861, 864
Show Details
Mannich; Koch
Chemische Berichte, 1942 , vol. 75, p. 803
Show Details
Schuscherina et al.
Vestnik Moskovskogo Universiteta, 1957 , vol. 12, # 6 p. 173,182
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 398,401; engl. Ausg. S. 401
反应条件
unter vermindertem Druck;
参考文献
Schuscherina et al.
Zhurnal Obshchei Khimii, 1956 , vol. 26, p. 750,574; engl. Ausg. S. 861, 864
Show Details
Schuscherina et al.
Vestnik Moskovskogo Universiteta, 1957 , vol. 12, # 6 p. 173,182
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 398,401; engl. Ausg. S. 401
反应条件
sodium hydroxide; dihydrogen peroxide
参考文献
Korshak,V.V. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1960 , vol. 30, p. 907 - 912,922 - 926
反应条件
1: 60 percent / P4S10 / pyridine / 8 h / Heating
2: 2.) 70percent HClO4 / 1.) et; 2.) glacial acetic acid
View Scheme
参考文献
Klimenko, S. K.; Antipova, I. V.; Kharchenko, V. G.
Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, p. 2044 - 2045
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 10 p. 2242 - 2243
反应条件
1: (+/-)-2-oxocyclohexanepropionic acid With chloroformic acid ethyl ester; triethylamine in diethyl ether
T=20°C; 0.75 h;
2: diazomethane in diethyl ether
T=0 - 10°C; 14 h;
参考文献
Muthusamy, Sengodagounder; Babu, Srinivasarao Arulananda; Gunanathan, Chidambaram; Suresh, Eringathodi; Dastidar, Parthasarathi
Bulletin of the Chemical Society of Japan, 2002 , vol. 75, # 4 p. 801 - 811
反应条件
1: (i) ClCO2Et, Et3N, Et2O, (ii) /BRN= 102415/
2: <Et3O>BF4 / CH2Cl2
View Scheme
参考文献
Mock,W.L.; Hartman,M.E.
Journal of Organic Chemistry, 1977 , vol. 42, p. 459 - 465
反应条件
1: (i) ClCO2Et, Et3N, Et2O, (ii) /BRN= 102415/
2: <Et3O>BF4 / CH2Cl2
3: (i) NaH, benzene, (ii) /BRN= 969135/
View Scheme
参考文献
Mock,W.L.; Hartman,M.E.
Journal of Organic Chemistry, 1977 , vol. 42, p. 459 - 465
反应条件
water
1.) benzene, 80 deg C, 8 h, 2.) benzene; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Klimenko, S. K.; Trushina, E. V.; Sorokin, N. N.; Yaskevich, N. N.; Bel'skii, V. K.
Russian Journal of Organic Chemistry, 1994 , vol. 30, # 3.1 p. 378 - 383
Zhurnal Organicheskoi Khimii, 1994 , vol. 30, # 3 p. 355 - 359
