3-(2-氧代-环己基)-丙酸合成路线 （共 30 条）
反应条件
hydrogenchloride; acetic acid in methanol
参考文献
Brichima S.p.A.
Patent: US4322547 A1, 1982 ;
反应条件
2: platinum; ethanol / Hydrogenation View Scheme
参考文献
Schuscherina et al.
Zhurnal Obshchei Khimii, 1956 , vol. 26, p. 750,574; engl. Ausg. S. 861, 864
反应条件
1: 80 percent / p-toluenesulfonic acid, acetic anhydride / benzene / 4 h / 0 °C 2: Br2 / CCl4 / 0.5 h / 0 °C 3: aq. NaHCO3 / CCl4 / 10 h 4: 80 percent / CH3SO3H, P2O5 / 2 h / 60 °C View Scheme
参考文献
Mandal, A.K.; Jawalkar, D.G.
Journal of Organic Chemistry, 1989 , vol. 54, # 10 p. 2364 - 2369
反应条件
T=30°C; 120 h; Rhodococcus sp. (SP 361), pH 7;
参考文献
Beard, Timothy; Cohen, Mark A.; Parratt, Julian S.; Turner, Nicholas J.; Crosby, John; Moilliet, Jock
Tetrahedron: Asymmetry, 1993 , vol. 4, # 6 p. 1085 - 1104
参考文献
Haworth; Mavin
Journal of the Chemical Society, 1933 , p. 1012,1015
反应条件
1: 7.6 g / dioxane / 12 h / Heating
2: 90 percent / potassium hydroxide / H2O / 4 h / 20 °C
View Scheme
参考文献
Muthusamy, Sengodagounder; Babu, Srinivasarao Arulananda; Gunanathan, Chidambaram; Suresh, Eringathodi; Dastidar, Parthasarathi
Bulletin of the Chemical Society of Japan, 2002 , vol. 75, # 4 p. 801 - 811
反应条件
1: p-toluenesulfonic acid / benzene / Heating
2: 7.6 g / dioxane / 12 h / Heating
3: 90 percent / potassium hydroxide / H2O / 4 h / 20 °C
View Scheme
参考文献
Muthusamy, Sengodagounder; Babu, Srinivasarao Arulananda; Gunanathan, Chidambaram; Suresh, Eringathodi; Dastidar, Parthasarathi
Bulletin of the Chemical Society of Japan, 2002 , vol. 75, # 4 p. 801 - 811
反应条件
1: 85 percent / t-BuOK / 2-methyl-propan-2-ol / 1.) reflux, 30 min, 2.) reflux, 2 h
2: aq. HCl / 48 h / Heating
3: Heating
View Scheme
参考文献
Green, Stuart P.; Whiting, Donald A.
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 10 p. 1027 - 1034
反应条件
potassium hydroxide
Erhitzen des Reaktionsprodukts;
参考文献
Mannich; Koch
Chemische Berichte, 1942 , vol. 75, p. 803
反应条件
1: ethanolic sodium ethylate
2: ethanolic KOH-solution / Erhitzen des Reaktionsprodukts
View Scheme
参考文献
Mannich; Koch
Chemische Berichte, 1942 , vol. 75, p. 803
