2,6-二氯-7-甲基嘌呤合成路线 （共 22 条）
反应条件
potassium carbonate in acetonitrile T=20°C; 70 h;
参考文献
WO2005/28479 A2, ;
Page/Page column 58 ;
反应条件
trichlorophosphate; phosphorus trichoride Substitution;
参考文献
Kochergin; Aleksandrova; Korsunskii
Chemistry of Heterocyclic Compounds, 2000 , vol. 36, # 1 p. 74 - 76
反应条件
phosphorus pentachloride; trichlorophosphate
参考文献
Journal of the American Chemical Society, , vol. 79, p. 6401,6405
参考文献
DE96925 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 5, p. 844
Chemische Berichte, , vol. 30, p. 2414
Chemische Berichte, , vol. 31, p. 545 Anm.
反应条件
phosphonium iodide; hydrogen iodide
参考文献
Bendich et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 6073,6076
反应条件
1: 80 percent / methanol / 2 h / 100 °C 2: 80 percent / various solvent(s) / 60 °C 3: 150 - 160 °C / Heating View Scheme
参考文献
Kowalska, Alicja; Maslankiewicz, Andrzej; Syrek, Barbara; Cieplinski, Piotr
Monatshefte fuer Chemie, 1985 , vol. 116, p. 341 - 352
反应条件
hydrogenchloride T=120 - 125°C;
参考文献
Kowalska, Alicja; Maslankiewicz, Andrzej; Syrek, Barbara; Cieplinski, Piotr
Monatshefte fuer Chemie, 1985 , vol. 116, p. 341 - 352
反应条件
in water 2 h; Heating;
参考文献
Krutovskikh, G. N.; Gornaeva, G. F.; Vartanyan, L. P.; Muravich-Aleksandr, Kh. L.; Pernikova, V. G.
Pharmaceutical Chemistry Journal, 1986 , vol. 20, # 7 p. 493 - 496
Khimiko-Farmatsevticheskii Zhurnal, 1986 , vol. 20, # 7 p. 839 - 842
参考文献
Boehringer and Soehne
Patent: DE96925 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 5, p. 846
Full Text Show Details
Fischer,E.
Chemische Berichte, 1897 , vol. 30, p. 2414
Chemische Berichte, 1898 , vol. 31, p. 545 Anm.
反应条件
ethanol; ammonia T=85 - 90°C;
参考文献
Adams; Whitmore
Journal of the American Chemical Society, 1945 , vol. 67, p. 1271
