N-(4-甲氧基苄基)-2-甲基-2-丙胺合成路线 （共 6 条）
反应条件
1.1: triethylamine / dichloromethane / 0 - 20 °C 1.2: 0.25 h / 20 °C 2.1: didodecanoyl peroxide / 1,2-dichloro-ethane / 4 h / Reflux 3.1: trifluoroacetic acid / 2.5 h / Reflux View Scheme
参考文献
Lopez-Valdez, German; Olguin-Uribe, Simon; Millan-Ortiz, Alejandra; Gamez-Montano, Rocio; Miranda, Luis D.
Tetrahedron, 2011 , vol. 67, # 14 p. 2693 - 2701
反应条件
1,4-diaza-bicyclo[2.2.2]octane; B(C6F5)2(2,4,6-trimethylphenyl); hydrogen in benzene-d6
T=20°C; P=3040.2 Torr; 42 h; Inert atmosphere;
参考文献
Eroes, Gabor; Nagy, Krisztina; Mehdi, Hasan; Papai, Imre; Nagy, Peter; Kiraly, Peter; Tarkanyi, Gabor; Soos, Tibor
Chemistry - A European Journal, 2012 , vol. 18, # 2 p. 574 - 585
反应条件
N-bromosuccinmide; triphenylphosphine in tetrahydrofuran
T=80°C; 1 h;
参考文献
Cheung, Wai-Hung; Zheng, Shi-Long; Yu, Wing-Yiu; Zhou, Guo-Chuan; Che, Chi-Ming
Organic Letters, 2003 , vol. 5, # 14 p. 2535 - 2538
反应条件
1: With 4 A molecular sieve in methanol
T=20°C; 2 h;
2: With sodium tetrahydroborate in methanol
T=0°C; 1 h; Further stages.;
参考文献
Ibarra-Rivera, Tannya R.; Gamez-Montano, Rocio; Miranda, Luis D.
Chemical Communications, 2007 , # 33 p. 3485 - 3487
反应条件
chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)]palladium(II); caesium carbonate in tetrahydrofuran; water
T=60°C; Suzuki-Miyaura cross-coupling reaction; 24 h; Inert atmosphere;
参考文献
Fleury-Bregeot, Nicolas; Raushel, Jessica; Sandrock, Deidre L.; Dreher, Spencer D.; Molander, Gary A.
Chemistry - A European Journal, 2012 , vol. 18, # 31 p. 9564 - 9570
参考文献
Clayden; Tchabanenko; Yasin; Turnbull
Synlett, 2001 , # 2 p. 302 - 304
