3-(2-氧代环十二烷基)丙酸合成路线 （共 7 条）
反应条件
sodium hydroxide in toluene
参考文献
Daicel, Ltd.
Patent: US4005107 A1, 1977 ;
反应条件
sodium hydroxide in toluene
参考文献
Daicel Ltd.
Patent: US4085274 A1, 1978 ;
反应条件
potassium hydroxide; dibenzo-18-crown-6 in toluene T=80 - 90°C; 6 h;
参考文献
Zakharkin, L. I.; Antonova, G. N.; Podvisotskaya, L. S.
Russian Chemical Bulletin, 1995 , vol. 44, # 12 p. 2418 - 2419
Izvestiya Akademi Nauk, Seriya Khimicheskaya, 1995 , # 12 p. 2521 - 2523
参考文献
Biemann et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 5558,5562
反应条件
hydrogenchloride; acetic acid 8 h; Heating;
参考文献
Zakharkin, L. I.; Churilova, I. M.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 10 p. 1895 - 1899
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 10 p. 2146 - 2150
反应条件
1: 86 percent / cyclohexylamine, acetic acid, hydroquinone / 120 - 200 °C 2: 93 percent / acetic acid, conc. HCl / 8 h / Heating View Scheme
参考文献
Zakharkin, L. I.; Churilova, I. M.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 10 p. 1895 - 1899
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 10 p. 2146 - 2150
反应条件
(i) O3, (ii) aq. H2O2; Multistep reaction;
参考文献
Bailey; Gilpin; Jones
Journal of the Chemical Society. Perkin transactions 1, 1977 , # 3 p. 265 - 270
