3-甲基苯并呋喃-2-碳酰氯合成路线 （共 4 条）
反应条件
thionyl chloride; benzene
参考文献
Acta Poloniae Pharmaceutica, , vol. 13, p. 11,19
Chem.Abstr., , p. 16671
反应条件
in dichloromethane; N,N-dimethyl-formamide T=20°C; 4 h;
参考文献
AFFINIUM PHARMACEUTICALS, INC.; PARTRIDGE, John, J.; COLUCCI, John; GAREAU, Yves; THERIEN, Michel; ZAMBONI, Robert; HAFKIN, Barry; MARFAT, Anthony; ZAGHDANE, Helmi
Patent: WO2013/190384 A1, 2013 ;
Location in patent: Paragraph 00202 ;
反应条件
triethylamine in tetrahydrofuran T=20°C;
参考文献
AXYS PHARMACEUTICALS, INC.
Patent: WO2005/118584 A2, 2005 ;
Location in patent: Page/Page column 80-81 ;
反应条件
1: dichloromethane / 2 h / 0 - 20 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / 5 h / 0 °C / |Heating; |Reflux
View Scheme
参考文献
AFFINIUM PHARMACEUTICALS, INC.; PARTRIDGE, John, J.; COLUCCI, John; GAREAU, Yves; THERIEN, Michel; ZAMBONI, Robert; HAFKIN, Barry; MARFAT, Anthony; ZAGHDANE, Helmi
Patent: WO2013/190384 A1, 2013 ;
