3(S)-碘甲基吡咯烷-1-羧酸叔丁酯合成路线 （共 2 条）
反应条件
1H-imidazole; iodine; triphenylphosphine in dichloromethane T=70°C; 3 h;
参考文献
DAINIPPON SUMITOMO PHARMA CO., LTD.; MIZUNO, Kazuhiro; IKEDA, Junya; NAKAMURA, Takanori; IWATA, Masato; OTAKA, Hiromichi; GOTO, Nana
Patent: WO2012/169649 A1, 2012 ;
Location in patent: Page/Page column 164; 165 ;
WO 2012/169649 A1
反应条件
1.1: dimethylsulfide borane complex / tetrahydrofuran / 3 h / 0 - 20 °C 1.2: 0 °C 2.1: 1H-imidazole; triphenylphosphine; iodine / dichloromethane / 3 h / 70 °C View Scheme
参考文献
DAINIPPON SUMITOMO PHARMA CO., LTD.; MIZUNO, Kazuhiro; IKEDA, Junya; NAKAMURA, Takanori; IWATA, Masato; OTAKA, Hiromichi; GOTO, Nana
Patent: WO2012/169649 A1, 2012 ;
WO 2012/169649 A1
