3,3,3-三氟-1-丙醇合成路线 （共 15 条）
反应条件
hydroxide T=24.85°C; P=760 Torr; KineticsProduct distribution;
参考文献
Kelly, Tanya; Bossoutrot, Valerie; Magneron, Isabelle; Wirtz, Klaus; Treacy, Jack; Mellouki, Abdelwahid; Sidebottom, Howard; Bras, Georges Le
Journal of Physical Chemistry A, 2005 , vol. 109, # 2 p. 347 - 355
反应条件
carbon tetrabromide; triphenylphosphine T=0°C; Reflux;
参考文献
Fontenelle, Clement Q.; Wang, Zhong; Fossey, Christine; Cailly, Thomas; Linclau, Bruno; Fabis, Frederic
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 23 p. 7529 - 7538
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran; toluene T=20°C; 43 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2006/67443 A1, 2006 ;
Location in patent: Page/Page column 50 ;
WO 2006/067443 A1
反应条件
hydroxide T=24.85°C; P=760 Torr; KineticsProduct distribution;
参考文献
Kelly, Tanya; Bossoutrot, Valerie; Magneron, Isabelle; Wirtz, Klaus; Treacy, Jack; Mellouki, Abdelwahid; Sidebottom, Howard; Bras, Georges Le
Journal of Physical Chemistry A, 2005 , vol. 109, # 2 p. 347 - 355
反应条件
sodium dichromate; sulfuric acid
参考文献
Henne et al.
Journal of the American Chemical Society, 1950 , vol. 72, p. 3370
