2,3-二氢-1H-茚-1-乙酸乙酯合成路线 （共 14 条）
反应条件
[NiCl2(1,2-dimethoxyethane)]; zinc; Pybox in methanol
T=40°C; 1 h;
参考文献
Kim, Hyejin; Lee, Chulbom
Organic Letters, 2011 , vol. 13, # 8 p. 2050 - 2053
反应条件
[NiCl2(1,2-dimethoxyethane)]; zinc; Pybox in methanol
T=40°C; 6 h;
参考文献
Kim, Hyejin; Lee, Chulbom
Organic Letters, 2011 , vol. 13, # 8 p. 2050 - 2053
反应条件
1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride in 1,2-dimethoxythane; mineral oil
T=0 - 20°C;
2: 1,3-dihydro-1-oxo-2H-indene in 1,2-dimethoxythane; mineral oil
T=0 - 20°C; Reflux;
3: With water in 1,2-dimethoxythane; mineral oil
T=20°C;
参考文献
ABBOTT LABORATORIES
Patent: US2012/122888 A1, 2012 ;
Location in patent: Page/Page column 49 ;
反应条件
palladium in ethyl acetate
参考文献
Pharmacia and Upjohn Company
Patent: US5877317 A1, 1999 ;
反应条件
palladium in ethanol
参考文献
Synthelabo
Patent: US5929078 A1, 1999 ;
US 5929078 A
反应条件
palladium on activated charcoal; ethanol
Hydrogenation;
参考文献
Anderson; Wade
Journal of the American Chemical Society, 1952 , vol. 74, p. 2274,2277
反应条件
1: Zn, HgCl2, I2 / benzene; diethyl ether / Heating
2: HCO2H
3: H2 / PtO2
View Scheme
参考文献
Anderson,A.G. et al.
Journal of Organic Chemistry, 1973 , vol. 38, # 8 p. 1439 - 1444
反应条件
1: HCO2H
2: H2 / PtO2
View Scheme
参考文献
Anderson,A.G. et al.
Journal of Organic Chemistry, 1973 , vol. 38, # 8 p. 1439 - 1444
反应条件
potassium hydroxide in ethanol
参考文献
Data; Taylor; Forcione
Journal of Pharmaceutical Sciences, 1974 , vol. 63, # 6 p. 848 - 853
反应条件
1: benzene
2: aq. KOH / ethanol
View Scheme
参考文献
Data; Taylor; Forcione
Journal of Pharmaceutical Sciences, 1974 , vol. 63, # 6 p. 848 - 853
