1,3-二(甲苯磺酰氧基)-2,2-二甲基丙烷合成路线 （共 12 条）
参考文献
Gobbi, Luca Claudio; Gubler, Marcel; Neidhart, Werner; Nettekoven, Matthias Heinrich
Patent: US2005/113374 A1, 2005 ;
Location in patent: Page/Page column 7; 14-15 ;
反应条件
potassium cyanide; sodium hydroxide in pyridine; methanol; dichloromethane; water; ethylene glycol; N,N-dimethyl-formamide
反应条件
sodium hydride 1) THF, 30 min, r.t., 2) THF, 6 h, reflux; Yield given. Multistep reaction;
参考文献
Chemische Berichte, , vol. 114, # 4 p. 1551 - 1553
反应条件
1: 71 percent / ethane-1,2-diol / 2 h / Heating 2: 85 percent / NaOH / H2O / 48 h / Heating 3: 89 percent / Thionyl chloride 4: 98 percent / NH3 / diethyl ether / 2 h View Scheme
参考文献
Wills, Max T.; Wills, Irene E.; Dollen, Lawrence Von; Butler, Barry L.; Porter, John; Anderson, Arthur G.
Journal of Organic Chemistry, 1980 , vol. 45, # 12 p. 2489 - 2498
反应条件
1: 71 percent / ethane-1,2-diol / 2 h / Heating 2: 85 percent / NaOH / H2O / 48 h / Heating View Scheme
参考文献
Brown,H.C. et al.
Journal of the American Chemical Society, 1977 , vol. 99, # 2 p. 505 - 509
反应条件
in ethylene glycol T=100°C; 1 h;
参考文献
Moss, Robert A.; Liu, Weiguo; Krogh-Jespersen, Karsten
Journal of Physical Chemistry, 1993 , vol. 97, p. 13413 - 13418
反应条件
in ethylene glycol 2 h; Heating;
参考文献
Wills, Max T.; Wills, Irene E.; Dollen, Lawrence Von; Butler, Barry L.; Porter, John; Anderson, Arthur G.
Journal of Organic Chemistry, 1980 , vol. 45, # 12 p. 2489 - 2498
反应条件
1: NaI 2: KOH 3: saponification 4: 180 °C View Scheme
参考文献
Park; Varick; Newcomb
Tetrahedron Letters, 1990 , vol. 31, # 21 p. 2975 - 2978
反应条件
1: benzene-1,2-diol With potassium carbonate in DMF (N,N-dimethyl-formamide) T=40°C; 1 h; 2: 2,2-dimethylpropane-1,3-diyl-bis-(4-methylbenzenesulfonate) in DMF (N,N-dimethyl-formamide) T=140°C; 5 h;
参考文献
Gobbi, Luca Claudio; Gubler, Marcel; Neidhart, Werner; Nettekoven, Matthias Heinrich
Patent: US2005/113374 A1, 2005 ;
Location in patent: Page/Page column 7; 11 ;
反应条件
1: NaI
2: KOH
3: saponification
4: 180 °C
5: LiAlH4
View Scheme
参考文献
Park; Varick; Newcomb
Tetrahedron Letters, 1990 , vol. 31, # 21 p. 2975 - 2978
