1,5,6,7-四氢-2H-氮杂卓-2-酮合成路线 （共 8 条）
参考文献
Donat; Nelson
Journal of Organic Chemistry, 1957 , vol. 22, p. 1107
反应条件
methanesulfonic acid; phosphorus pentoxide T=110°C; 2 h;
参考文献
Mueller, Alexander; Takyar, Dinesh K.; Witt, Sandra; Koenig, Wilfried A.
Liebigs Annalen der Chemie, 1993 , # 6 p. 651 - 656
反应条件
1.1: lithium hexamethyldisilazane / tetrahydrofuran / -40 °C / |Inert atmosphere 2.1: lithium hexamethyldisilazane; benzeneselenenyl chloride / tetrahydrofuran / -78 °C / |Inert atmosphere 2.2: 0 °C / |Inert atmosphere 3.1: trifluoroacetic acid / dichloromethane / 20 °C / |Inert atmosphere View Scheme
参考文献
Alvarez, Silvia; Dominguez, Gema; Gradillas, Ana; Perez-Castells, Javier
European Journal of Organic Chemistry, 2013 , # 15 p. 3094 - 3102
反应条件
1.1: lithium hexamethyldisilazane; benzeneselenenyl chloride / tetrahydrofuran / -78 °C / |Inert atmosphere 1.2: 0 °C / |Inert atmosphere 2.1: trifluoroacetic acid / dichloromethane / 20 °C / |Inert atmosphere View Scheme
参考文献
Alvarez, Silvia; Dominguez, Gema; Gradillas, Ana; Perez-Castells, Javier
European Journal of Organic Chemistry, 2013 , # 15 p. 3094 - 3102
反应条件
methanol; high silica zeolite T=380°C; Beckmann Rearrangement;
参考文献
Sumitomo Chemical Company, Limited
Patent: EP1167350 A1, 2002 ;
Location in patent: Paragraph [0056] - [0059] ;
反应条件
1: 35 percent / NH2OH*HCl, NaOAc / H2O / 1 h / 60 °C 2: 15 percent / P2O5, methanesulfonic acid / 2 h / 110 °C View Scheme
参考文献
Mueller, Alexander; Takyar, Dinesh K.; Witt, Sandra; Koenig, Wilfried A.
Liebigs Annalen der Chemie, 1993 , # 6 p. 651 - 656
参考文献
Strishakow et al.
Zhurnal Obshchei Khimii, 1965 , vol. 35, p. 628,630; engl. Ausg. S. 631, 632
反应条件
lithium aluminium tetrahydride; sulfuric acid in tetrahydrofuran T=0°C; 0.5 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Liebigs Annalen der Chemie, , # 6 p. 651 - 656
