(E)-3-(4-甲氧基苯基)-1-苯基-丙-2-烯-1-酮合成路线 （共 63 条）
反应条件
aluminium trichloride
0.25 h; microwave irradiation;
参考文献
Huang, Danfeng; Wang, Jin-Xian; Hu, Yulai; Zhang, Yumei; Tang, Jing
Synthetic Communications, 2002 , vol. 32, # 7 p. 971 - 979
反应条件
ReOCl3(SMe2)(OPPh3); water in ethylene glycol dimethyl ether; hexane
T=80°C; Meyer-Schuster Rearrangement; 4.5 h; Inert atmosphere; stereoselective reaction;
参考文献
Mattia, Elio; Porta, Alessio; Merlini, Valentina; Zanoni, Giuseppe; Vidari, Giovanni
Chemistry - A European Journal, 2012 , vol. 18, # 38 p. 11894 - 11898
反应条件
ytterbium(III) triflate in tetrahydrofuran; dichloromethane
T=0 - 20°C; Condensation; aldol reaction; 2.5 h;
参考文献
Graven, Anette; Grotli, Morten; Meldal, Morten
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 6 p. 955 - 962
反应条件
sodium hydroxide in methanol
T=20°C;
参考文献
Rokade, Balaji V.; Gadde, Karthik; Prabhu, Kandikere Ramaiah
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 5 p. 946 - 950
反应条件
1: 98 percent / triethylamine / tetrahydrofuran / 0.5 h / 0 - 20 °C
2: t-BuOK / tetrahydrofuran / 0.17 h / -78 °C
3: 76 percent / aq. sulfuric acid / tetrahydrofuran; 1,2-dimethoxy-ethane / 0.17 h / -78 °C
View Scheme
参考文献
Yoshizawa, Kazuhiro; Shioiri, Takayuki
Tetrahedron, 2007 , vol. 63, # 27 p. 6259 - 6286
反应条件
1.1: n-BuLi / hexane; tetrahydrofuran / 0.17 h / -78 °C
1.2: 87 percent / tetrahydrofuran; hexane / 1 h / -78 - 20 °C
2.1: 98 percent / triethylamine / tetrahydrofuran / 0.5 h / 0 - 20 °C
3.1: t-BuOK / tetrahydrofuran / 0.17 h / -78 °C
4.1: 76 percent / aq. sulfuric acid / tetrahydrofuran; 1,2-dimethoxy-ethane / 0.17 h / -78 °C
View Scheme
参考文献
Yoshizawa, Kazuhiro; Shioiri, Takayuki
Tetrahedron, 2007 , vol. 63, # 27 p. 6259 - 6286
反应条件
1.1: n-BuLi / hexane; tetrahydrofuran / 0.17 h / -78 °C
1.2: 87 percent / tetrahydrofuran; hexane / 1 h / -78 - 20 °C
2.1: 98 percent / triethylamine / tetrahydrofuran / 0.5 h / 0 - 20 °C
3.1: t-BuOK / tetrahydrofuran / 0.17 h / -78 °C
4.1: 76 percent / aq. sulfuric acid / tetrahydrofuran; 1,2-dimethoxy-ethane / 0.17 h / -78 °C
View Scheme
参考文献
Yoshizawa, Kazuhiro; Shioiri, Takayuki
Tetrahedron, 2007 , vol. 63, # 27 p. 6259 - 6286
反应条件
1.1: potassium carbonate / butanone / 0.5 h / 60 - 65 °C
1.2: Reflux
2.1: sodium hydroxide / ethanol; water / 0.5 h / 20 °C / Cooling with ice
View Scheme
参考文献
Hasan, Aurangzeb; Abbas, Asghar; Akhtar, Muhammed Nadeem
Molecules, 2011 , vol. 16, # 9 p. 7789 - 7802
反应条件
1.1: n-butyllithium / hexane; ethylene glycol dimethyl ether / 1 h / -78 °C / |Inert atmosphere
1.2: 1.5 h / -78 °C / |Inert atmosphere
1.3: 20 °C / |Inert atmosphere
2.1: ReOCl3(SMe2)(OPPh3); water / hexane; ethylene glycol dimethyl ether / 4.5 h / 80 °C / |Inert atmosphere
View Scheme
参考文献
Mattia, Elio; Porta, Alessio; Merlini, Valentina; Zanoni, Giuseppe; Vidari, Giovanni
Chemistry - A European Journal, 2012 , vol. 18, # 38 p. 11894 - 11898
反应条件
sodium ethanolate in ethanol
Heating;
参考文献
Darwish, A. I.
Egyptian Journal of Chemistry, 2002 , vol. 45, # 4 p. 695 - 711
