(E)-3-(4-甲氧基苯基)-1-苯基-丙-2-烯-1-酮合成路线 （共 63 条）
反应条件
hydrogenchloride; n-butyllithium 1) THF, hexane, -78 degC; 2) THF, 20 degC; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Amberg, Willi; Seebach, Dieter
Angewandte Chemie, 1988 , vol. 100, # 12 p. 1786 - 1787
反应条件
hydrogenchloride; n-butyllithium 1.) THF, hexane, -78 deg C, 2.) THF, 0 deg C, 10 min; Yield given. Multistep reaction;
参考文献
Amberg, Willi; Seebach, Dieter
Chemische Berichte, 1990 , vol. 123, # 12 p. 2439 - 2444
反应条件
sodium hydroxide in ethanol
T=20°C;
参考文献
Kellogg, Richard M.; Nieuwenhuijzen, Jose W.; Pouwer; Vries, Ton R.; Broxterman, Quirinus B.; Grimbergen, Reinier F.P.; Kaptein, Bernard; La Crois, Rene M.; De Wever, Ellen; Zwaagstra, Karen; Van Der Laan, Alexander C.
Synthesis, 2003 , # 10 p. 1626 - 1638
反应条件
copper(I) thiophene-2-carboxylate; triphenylphosphine; bis(dibenzylideneacetone)-palladium(0) in diethyl ether
T=20°C; 3 h; Schlenk techniqueInert atmosphere;
参考文献
Ogawa, Daisuke; Hyodo, Keita; Suetsugu, Masato; Li, Jing; Inoue, Yoshiaki; Fujisawa, Mamoru; Iwasaki, Masayuki; Takagi, Kentaro; Nishihara, Yasushi
Tetrahedron, 2013 , vol. 69, # 12 p. 2565 - 2571
反应条件
amberlyst-15 resin
T=90°C; Microwave irradiationNeat (no solvent);
参考文献
Rueping, Magnus; Bootwicha, Teerawut; Baars, Hannah; Sugiono, Erli
Beilstein Journal of Organic Chemistry, 2011 , vol. 7, p. 1680 - 1687
反应条件
N-ethyl-N,N-diisopropylamine; tri-cyclo-hexyl-phosphine; tris(dibenzylideneacetone)dipalladium (0) in tetrahydrofuran
T=150°C; Suzuki cross-coupling; 0.2 h; microwave irradiation;
参考文献
Buszek, Keith R.; Brown, Neil
Organic Letters, 2007 , vol. 9, # 4 p. 707 - 710
反应条件
copper(l) iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran
T=120°C; 0.5 h; microwave irradiation;
参考文献
Schramm, Oana G.; Mueller, Thomas J. J.
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 18 p. 2565 - 2570
反应条件
trichlorosilane; triethylamine; triphenyl-phosphine oxide in dichloromethane
T=-10 - 20°C;
参考文献
Smith, James M.; Greaney, Michael F.
Tetrahedron Letters, 2007 , vol. 48, # 49 p. 8687 - 8690
反应条件
triethylamine; triphenylphosphine; palladium dichloride in 1,4-dioxane
T=80°C; 4 h;
参考文献
Rao, Maddali L.N.; Venkatesh, Varadhachari; Jadhav, Deepak N.
Journal of Organometallic Chemistry, 2008 , vol. 693, # 15 p. 2494 - 2498
反应条件
N,N-dimethyl-formamide in hydrogen fluoride
T=160°C; 1.5 h;
参考文献
Khurana; Maikap; Sahoo
Synthesis, 1991 , # 10 p. 827 - 828
