2,3,4-三甲氧基-6-羟基苯乙酮合成路线 （共 42 条）
反应条件
1: With zinc(II) chloride in nitromethane Friedel-Crafts reaction; 2: With sodium hydrogencarbonate in nitromethane Further stages.;
参考文献
Igarashi, Yasushi; Kumazawa, Hiroaki; Ohshima, Toshihoro; Satomi, Hisanori; Terabayashi, Susumu; Takeda, Shuichi; Aburada, Masaki; Miyamoto, Ken-Ichi
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 9 p. 1088 - 1091
反应条件
1: 3,4,5-trimethoxyphenol With boron trifluoride diethyl etherate 0.25 h; Heating / reflux; 2: benzaldehyde With potassium hydroxide in ethanol; water T=15 - 20°C; 8 h; 3: With hydrogenchloride in water
参考文献
Unitech Pharmaceuticals, Inc.
Patent: US2004/242907 A1, 2004 ;
Location in patent: Page 2 ;
反应条件
boron trifluoride diethyl etherate T=70°C; 2 h;
参考文献
Gao, Hong; Nishida, Jun; Saito, Shizuka; Kawabata, Jun
Molecules, 2007 , vol. 12, # 1 p. 86 - 97
反应条件
1: 3,4,5-trimethoxyphenol; acetic anhydride With bismuth trifluoromethanesulphonate in toluene T=20°C; 0.0833333 h; Inert atmosphere; 2: isoprene in toluene T=40°C; 4 h; Inert atmosphereSealed tube; 3: With methanol; potassium carbonate T=20°C; 0.833333 h;
参考文献
Judd, Katie E.; Caggiano, Lorenzo
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 14 p. 5201 - 5210
反应条件
1: 96 percent / AcONa / 3 h / 110 °C 2: 94 percent / BF3*Et2O / 2 h / 70 °C View Scheme
参考文献
Oliverio; Bargellini
Gazzetta Chimica Italiana, 1948 , vol. 78, p. 386,394
反应条件
potassium carbonate in acetone Heating;
参考文献
Horie, Tokunaru; Tsukayama, Masao; Kourai, Hiroki; Yokoyama, Chieko; Furukawa, Masayuki; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2256 - 2262
反应条件
1: K2CO3 / acetone / 10 h / Heating 2: 50percent KOH / ethanol / 120 h / Heating View Scheme
参考文献
Quijano, Leovigildo; Calderon, Jose S.; Garibay, Frederico Gomez; Escobar, Edgar; Rios, Tirso
Phytochemistry (Elsevier), 1987 , vol. 26, # 7 p. 2075 - 2078
反应条件
potassium carbonate; benzene
参考文献
Oliverio; Bargellini
Gazzetta Chimica Italiana, 1948 , vol. 78, p. 386,394
Full Text Show Details
Rabjohn; Rosenburg
Journal of Organic Chemistry, 1959 , vol. 24, p. 1192,1195
Full Text Show Details
Sastri; Seshadri
Proceedings - Indian Academy of Sciences, Section A, 1946 , vol. 23, p. 262,266
Full Text Show Details
Baker
Journal of the Chemical Society, 1941 , p. 662,669
参考文献
Huang, Wen-Hsin; Chien, Pei-Yu; Yang, Ching-Huey; Lee, An-Rong
Chemical and pharmaceutical bulletin, 2003 , vol. 51, # 3 p. 339 - 340
反应条件
potassium carbonate in acetone 3 h; Heating;
参考文献
Hossain, M. Amzad; Ismail, Zhari
Pakistan Journal of Scientific and Industrial Research, 2008 , vol. 51, # 1 p. 11 - 14
