8-硝基-1,3,4,5-四氢-2H-1-苯并吖庚因-2-酮合成路线 (共 11 条)
反应条件
polyphosphoric acid T=125°C; 16 h;
参考文献
SANOFI; CARRY, Jean-Christophe; CHATREAUX, Fabienne; DEPRETS, Stéphanie; DUCLOS, Olivier; LEROY, Vincent; MALLART, Sergio; MELON-MANGUER, Dominique; MENDEZ-PEREZ, Maria; VERGNE, Fabrice
Patent: WO2013/150036 A1, 2013 ;
Location in patent: Page/Page column 111 ;
反应条件
sodium hydroxide; sodium azide in acetic acid
反应条件
sulfuric acid; nitric acid Title compound not separated from byproducts;
参考文献
Osadchii, S. A.; Kochubei, N. V.
Russian Journal of Applied Chemistry, 1994 , vol. 67, # 11.2 p. 1674 - 1676
Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1994 , vol. 67, # 11 p. 1909 - 1911
反应条件
1: nitric acid; sulfuric acid / water / 1.5 h / 0 - 20 °C 2: hydroxylamine hydrochloride; sodium acetate / water; ethanol / 1 h / |Reflux 3: polyphosphoric acid / 16 h / 125 °C View Scheme
反应条件
1: hydroxylamine hydrochloride; sodium acetate / water; ethanol / 1 h / |Reflux 2: polyphosphoric acid / 16 h / 125 °C View Scheme
参考文献
Chemische Berichte, , vol. 49, p. 808
反应条件
1: polyphosphoric acid 2: HNO3,H2SO4 View Scheme
参考文献
Russian Journal of Applied Chemistry, , vol. 67, # 11.2 p. 1674 - 1676
Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), , vol. 67, # 11 p. 1909 - 1911
反应条件
1: sulfuric acid / beim Nitrieren 2: hydrochloric acid 3: mineral acids View Scheme
参考文献
Chemische Berichte, , vol. 49, p. 808
参考文献
Chemische Berichte, , vol. 49, p. 808
反应条件
1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 16 h / 20 °C 2: palladium 10 on activated carbon; ammonium formate / methanol / 0.08 h / -8 °C / |Microwave irradiation View Scheme
参考文献
SANOFI; CARRY, Jean-Christophe; CHATREAUX, Fabienne; DEPRETS, Stéphanie; DUCLOS, Olivier; LEROY, Vincent; MALLART, Sergio; MELON-MANGUER, Dominique; MENDEZ-PEREZ, Maria; VERGNE, Fabrice
Patent: WO2013/150036 A1, 2013 ;