6-羟基-3,4-二氢异喹啉-1(2H)-酮合成路线

百科

结构式

环氧丙烷冰醋酸 63148-62-9 MDI 丁酮二甲基亚砜碳酸氢钠 471-34-1

6-羟基-3,4-二氢异喹啉-1(2H)-酮合成路线（共 7 条）

22246-12-46-甲氧基-3,4-二氢-1(2H)-异喹啉→22245-98-36-羟基-3,4-二氢异喹啉-1(2H)-酮

参考文献

Fu, Liqiang; Liu, Xin; Ling, Chenyu; Cheng, Jianjun; Guo, Xingsheng; He, Huili; Ding, Shi; Yang, Yushe
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 814 - 819

3470-49-35-羟基-1-茚酮→22245-98-36-羟基-3,4-二氢异喹啉-1(2H)-酮

参考文献

PHARMACOPEIA DRUG DISCOVERY, INC.
Patent: WO2007/1249 A1, 2007 ;
Location in patent: Page/Page column 52-53 ;

33543-63-43-甲氧基苯乙基氨基甲酸乙酯→22245-98-36-羟基-3,4-二氢异喹啉-1(2H)-酮

参考文献

Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 2 p. 814 - 819

2039-67-03-甲氧基苯乙胺→22245-98-36-羟基-3,4-二氢异喹啉-1(2H)-酮

参考文献

Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 2 p. 814 - 819

5111-70-65-甲氧基-1-茚酮→22245-98-36-羟基-3,4-二氢异喹啉-1(2H)-酮

参考文献

Journal of Medicinal Chemistry, , vol. 55, # 5 p. 2452 - 2468

22245-98-36-羟基-3,4-二氢异喹啉-1(2H)-酮+100-39-0溴化苄→164147-66-4

参考文献

Fisher, Matthew J.; Gunn, Bruce; Harms, Cathy S.; Kline, Allen D.; Mullaney, Jeffrey T.; Nunes, Anne; Scarborough, Robert M.; Arfsten, Ann E.; Skelton, Marshall A.; Um, Suzane L.; Utterback, Barbara G.; Jakubowski, Joseph A.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 13 p. 2085 - 2101

22245-98-36-羟基-3,4-二氢异喹啉-1(2H)-酮+421-83-0三氟甲烷磺酰氯→897374-38-8

参考文献

DECIPHERA PHARMACEUTICALS, LLC
Patent: WO2006/71940 A2, 2006 ;
Location in patent: Page/Page column 420 ;
WO 2006/071940 A2