7-氨基-1,3,4,5-四氢-苯并[B]氮杂革-2-酮合成路线 （共 7 条）
反应条件
hydrazine hydrate; Pd/C in ethanol 0.5 h; Heating;
参考文献
Osadchii, S. A.; Kochubei, N. V.
Russian Journal of Applied Chemistry, 1994 , vol. 67, # 11.2 p. 1674 - 1676
Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1994 , vol. 67, # 11 p. 1909 - 1911
反应条件
1: T=90 - 120°C; 4.5 h; 2: With water T=0°C; 0.5 h; 3: With sodium hydroxide in water T=90°C;
参考文献
Camus, Laure; Chudasama, Reshma; Day, Caroline Jane; Deshmukh, Deepali; Gleason, John Gerald; Harling, John David; Lee, Chao-Pin; Saklatvala, Paula; Senger, Stefan; Vallance, Sarah; Watson, John; Watson, Nigel Stephen; Young, Robert John; Yuan, Barbara
Patent: US2008/306045 A1, 2008 ;
Location in patent: Page/Page column 13 ;
反应条件
1: 60 percent / HNO3,H2SO4 2: 96 percent / 95percent N2H4*H2O / 4percentPd,C / ethanol / 0.5 h / Heating View Scheme
参考文献
Weinberg, Linda R.; Albom, Mark S.; Angeles, Thelma S.; Husten, Jean; Lisko, Joseph G.; McHugh, Robert J.; Milkiewicz, Karen L.; Murthy, Seetha; Ott, Gregory R.; Theroff, Jay P.; Tripathy, Rabindranath; Underiner, Ted L.; Zificsak, Craig A.; Dorsey, Bruce D.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 164 - 167
反应条件
1: polyphosphoric acid 2: 60 percent / HNO3,H2SO4 3: 96 percent / 95percent N2H4*H2O / 4percentPd,C / ethanol / 0.5 h / Heating View Scheme
参考文献
Osadchii, S. A.; Kochubei, N. V.
Russian Journal of Applied Chemistry, 1994 , vol. 67, # 11.2 p. 1674 - 1676
Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1994 , vol. 67, # 11 p. 1909 - 1911
反应条件
2: polyphosphoric acid 3: 60 percent / HNO3,H2SO4 4: 96 percent / 95percent N2H4*H2O / 4percentPd,C / ethanol / 0.5 h / Heating View Scheme
参考文献
Osadchii, S. A.; Kochubei, N. V.
Russian Journal of Applied Chemistry, 1994 , vol. 67, # 11.2 p. 1674 - 1676
Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1994 , vol. 67, # 11 p. 1909 - 1911
参考文献
Buege, Axel; Locke, Christian; Koehler, Thomas; Nuhn, Peter
Archiv der Pharmazie (Weinheim, Germany), 1994 , vol. 327, # 2 p. 99 - 104
参考文献
Buege, Axel; Locke, Christian; Koehler, Thomas; Nuhn, Peter
Archiv der Pharmazie (Weinheim, Germany), 1994 , vol. 327, # 2 p. 99 - 104
