4,6-二甲氧基呋喃并[2,3-b]喹啉合成路线 （共 16 条）
反应条件
potassium hydrogensulfate in tetrahydrofuran
参考文献
Yazima; Munakata
Agricultural and Biological Chemistry, 1980 , vol. 44, # 2 p. 235 - 243
反应条件
1: (5R,6S)-4-methoxy-5,6-dihydrofuro[2,3-b]quinoline-5,6-diol With trifluoroacetic acid in chloroform-d1
T=50°C;
2: diazomethane
参考文献
Boyd, Derek R.; Sharma, Narain D.; Carroll, Jonathan G.; Loke, Pui L.; O'Dowd, Colin R.; Allen, Christopher C. R.
RSC Advances, 2013 , vol. 3, # 27 p. 10944 - 10955
参考文献
Boyd, Derek R.; Sharma, Narain D.; O'Dowd, Colin R.; Carroll, Jonathan G.; Loke, Pui L.; Allen, Christopher C. R.
Chemical Communications, 2005 , # 31 p. 3989 - 3991
反应条件
1: NaH; DMSO / tetrahydrofuran / 0.5 h / 0 - 20 °C
2: polyphosphoric acid / 2 h / 125 - 130 °C
View Scheme
参考文献
Bhoga, Umadevi; Mali; Adapa, Srinivas R.
Tetrahedron Letters, 2004 , vol. 45, # 51 p. 9483 - 9485
反应条件
1: n-BuLi / diethyl ether / 1 h / 0 - 20 °C
2: NaH; DMSO / tetrahydrofuran / 0.5 h / 0 - 20 °C
3: polyphosphoric acid / 2 h / 125 - 130 °C
View Scheme
参考文献
Bhoga, Umadevi; Mali; Adapa, Srinivas R.
Tetrahedron Letters, 2004 , vol. 45, # 51 p. 9483 - 9485
反应条件
1: 94 percent / dioxane; methanol
2: 90 percent / NaBH4
3: 80 percent / KHSO4 / tetrahydrofuran
View Scheme
参考文献
Yazima; Munakata
Agricultural and Biological Chemistry, 1980 , vol. 44, # 2 p. 235 - 243
反应条件
1: 94 percent / paraffin / 0.17 h / 250 °C
2: 94 percent / dioxane; methanol
3: 90 percent / NaBH4
4: 80 percent / KHSO4 / tetrahydrofuran
View Scheme
参考文献
Yazima; Munakata
Agricultural and Biological Chemistry, 1980 , vol. 44, # 2 p. 235 - 243
反应条件
1: Sphingomonas yanoikuyae B8/36 / |Microbiological reaction
2: trifluoroacetic acid / chloroform-d1 / 50 °C
View Scheme
参考文献
Boyd, Derek R.; Sharma, Narain D.; Carroll, Jonathan G.; Loke, Pui L.; O'Dowd, Colin R.; Allen, Christopher C. R.
RSC Advances, 2013 , vol. 3, # 27 p. 10944 - 10955
反应条件
1: sodium methylate / 2 h / |Reflux; |Inert atmosphere
2: Sphingomonas yanoikuyae B8/36 / |Microbiological reaction
3: trifluoroacetic acid / chloroform-d1 / 50 °C
View Scheme
参考文献
Boyd, Derek R.; Sharma, Narain D.; Carroll, Jonathan G.; Loke, Pui L.; O'Dowd, Colin R.; Allen, Christopher C. R.
RSC Advances, 2013 , vol. 3, # 27 p. 10944 - 10955
反应条件
PPA
T=125 - 130°C; 2 h;
参考文献
Bhoga, Umadevi; Mali; Adapa, Srinivas R.
Tetrahedron Letters, 2004 , vol. 45, # 51 p. 9483 - 9485
