(S)-(-)-1-苯基-1-丁醇合成路线 （共 63 条）
反应条件
sodium tetrahydroborate; third-generation glucose-persubstituted amidoamine dendrimer in tetrahydrofuran T=25°C;
参考文献
Stegink, Bart; Van Boxtel, Lonneke; Lefort, Laurent; Minnaard, Adriaan J.; Feringa, Ben L.; De Vries, Johannes G.
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 14-15 p. 2621 - 2628
反应条件
D-glucose; D-glucose dehydrogenase; Sporobolomyces salmonicolor carbonyl reductase; NADPH in phosphate buffer; dimethyl sulfoxide T=20°C; pH=6.5 - 6.6; Title compound not separated from byproducts;
参考文献
Zhu, Dunming; Hua, Ling
Journal of Organic Chemistry, 2006 , vol. 71, # 25 p. 9484 - 9486
反应条件
BF3·2HOAc; triethylamine; 3-chloro-benzenecarboperoxoic acid Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Chemical Communications, , # 18 p. 1456 - 1457
反应条件
potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate 15 h; Ambient temperature;
参考文献
Chan, T. H.; Pellon, P.
Journal of the American Chemical Society, 1989 , vol. 111, # 23 p. 8737 - 8738
反应条件
1: dimethylaluminium chloride / CH2Cl2; hexane / 24 h / 20 °C 2: 93 percent / various solvent(s) / 12 h / 20 °C 3: Raney nickel / ethanol / 24 h / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 122, # 9 p. 1927 - 1936
反应条件
1: SnCl4 / acetonitrile / -15 °C 2: H2 / Pd-Pb-CaCO3 3: PCC 4: 1.) MCPBA, 2.) p-TSA*pyridine, MeOH View Scheme
参考文献
Journal of the American Chemical Society, , vol. 104, # 25 p. 7371 - 7372
反应条件
sodium isopropanolate; acetone; [RuCl2(PPh3)(ferrocenyloxazolinylphosphine)] in isopropyl alcohol T=50°C; 0.5 h;
参考文献
Journal of Organic Chemistry, , vol. 68, # 15 p. 5875 - 5880
反应条件
titanium(IV) isopropylate in diethyl ether; dichloromethane T=0°C; 1 h; Title compound not separated from byproducts.;
参考文献
Muramatsu, Yusuke; Harada, Toshiro
Angewandte Chemie - International Edition, 2008 , vol. 47, # 6 p. 1088 - 1090
反应条件
1: n-propyl-magnesium chloride With sodium methylate; zinc(II) chloride in diethyl ether T=0°C; Inert atmosphere; 2: benzaldehyde With (S)-N-(3-methyl-1-(1-pyrrolidin-1-yl)butan-2-yl)-P,P-di(naphthalen-1-yl)phosphinic amideamine T=20°C; 2 h; Neat (no solvent); optical yield given as percent eeenantioselective reaction;
参考文献
Hatano, Manabu; Mizuno, Tomokazu; Ishihara, Kazuaki
Synlett, 2010 , # 13 p. 2024 - 2028
反应条件
(1S,2R)-(+)-N,N-dimethylephedrinium bis(trifluoromethanesulfon)imidate in dichloromethane T=120°C;
参考文献
Analytical Chemistry, , vol. 76, # 22 p. 6819 - 6822
