5-氯-N,N-二甲基色胺合成路线 （共 9 条）
反应条件
sulfuric acid 2 h; Heating;
参考文献
Chen; Senanayake; Bill; Larsen; Verhoeven; Reider
Journal of Organic Chemistry, 1994 , vol. 59, # 13 p. 3738 - 3741
反应条件
1: 5-Chlorotryptamine With vinylsulfonylmethyl polystyrene in N,N-dimethyl-formamide 2: methyl iodide in N,N-dimethyl-formamide 3: With N-ethyl-N,N-diisopropylamine in dichloromethane Hoffman elimination; Further stages.;
参考文献
Wu, Tom Y. H.; Schulte, Peter G.
Organic Letters, 2002 , vol. 4, # 23 p. 4033 - 4035
反应条件
sodium methylate; sodium cyanoborohydride; acetic acid in methanol; water T=20°C;
参考文献
Qu, Shi-Jin; Wang, Gui-Feng; Duan, Wen-Hu; Yao, Shan-Yan; Zuo, Jian-Ping; Tan, Chang-Heng; Zhu, Da-Yuan
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 10 p. 3120 - 3127
反应条件
hydrogenchloride Ambient temperature;
参考文献
Somei, Masanori; Kobayashi, Kensuke; Tanii, Keiko; Mochizuki, Toshihiko; Kawada, Yumiko; Fukui, Yoshikazu
Heterocycles, 1995 , vol. 40, # 1 p. 119 - 122
反应条件
1: 87 percent 2: 70 percent / LiAlH4 3: 92 percent / triethylsilane, CF3COOH 4: 55 percent / Na2WO4*2H2O, 30percent H2O2 / methanol; H2O 5: 55 percent / aq. HCl / Ambient temperature View Scheme
参考文献
Somei, Masanori; Kobayashi, Kensuke; Tanii, Keiko; Mochizuki, Toshihiko; Kawada, Yumiko; Fukui, Yoshikazu
Heterocycles, 1995 , vol. 40, # 1 p. 119 - 122
反应条件
1: 92 percent / triethylsilane, CF3COOH 2: 55 percent / Na2WO4*2H2O, 30percent H2O2 / methanol; H2O 3: 55 percent / aq. HCl / Ambient temperature View Scheme
参考文献
Somei, Masanori; Kobayashi, Kensuke; Tanii, Keiko; Mochizuki, Toshihiko; Kawada, Yumiko; Fukui, Yoshikazu
Heterocycles, 1995 , vol. 40, # 1 p. 119 - 122
反应条件
1: 70 percent / LiAlH4 2: 92 percent / triethylsilane, CF3COOH 3: 55 percent / Na2WO4*2H2O, 30percent H2O2 / methanol; H2O 4: 55 percent / aq. HCl / Ambient temperature View Scheme
参考文献
Somei, Masanori; Kobayashi, Kensuke; Tanii, Keiko; Mochizuki, Toshihiko; Kawada, Yumiko; Fukui, Yoshikazu
Heterocycles, 1995 , vol. 40, # 1 p. 119 - 122
反应条件
1: 55 percent / Na2WO4*2H2O, 30percent H2O2 / methanol; H2O 2: 55 percent / aq. HCl / Ambient temperature View Scheme
参考文献
Somei, Masanori; Kobayashi, Kensuke; Tanii, Keiko; Mochizuki, Toshihiko; Kawada, Yumiko; Fukui, Yoshikazu
Heterocycles, 1995 , vol. 40, # 1 p. 119 - 122
反应条件
sodium cyanoborohydride; acetic acid in methanol pH=6.5; 2 h; Reflux;
参考文献
Nirogi, Ramakrishna V.S.; Kambhampati, Ramasastri; Kothmirkar, Prabhakar; Konda, Jagadishbabu; Bandyala, Thrinath Reddy; Gudla, Parandhama; Arepalli, Sobhanadri; Gangadasari, Narasimhareddy P.; Shinde, Anil K.; Deshpande, Amol D.; Dwarampudi, Adireddy; Chindhe, Anil K.; Dubey, Pramod Kumar
Journal of Enzyme Inhibition and Medicinal Chemistry, 2012 , vol. 27, # 3 p. 443 - 450
