N-alpha-Cbz-L-赖氨酸合成路线 （共 34 条）
反应条件
(i) aq. NaOH, (ii) /BRN= 509751/, (iii) aq. HCl; Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 83, p. 719 - 722
反应条件
trifluoroacetic acid T=10 - 15°C;
参考文献
Journal of the American Chemical Society, , vol. 104, # 16 p. 4446 - 4450
反应条件
1.1: aq. LiOH / 0 °C 2.1: aq. NaOH / ethanol / 0.33 h / -10 - 20 °C 2.2: HCl / ethanol / 0.17 h / 50 °C View Scheme
参考文献
Organic Letters, , vol. 6, # 21 p. 3781 - 3784
反应条件
hydrogenchloride; bromocyane in tetrahydrofuran T=47°C; 4 h; Inert atmosphere;
参考文献
Journal of the American Chemical Society, , vol. 134, # 47 p. 19463 - 19467
反应条件
subtilisin 8350 in water T=25°C; kobs, kcat, and Km; pH 8.2; Rate constant;
参考文献
Journal of the American Chemical Society, , vol. 112, # 3 p. 945 - 953
反应条件
1: 94 percent / aq. alkali 2: TFA / 10 - 15 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 104, # 16 p. 4446 - 4450
反应条件
1: 94 percent / aq. alkali 2: TFA / 10 - 15 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 104, # 16 p. 4446 - 4450
反应条件
1: 1M NaOH / ethanol / -20 - -5 °C 2: 0.275 mol / HCl / ethanol / 0.08 h / 50 °C View Scheme
参考文献
Synthetic Communications, , vol. 32, # 13 p. 2075 - 2082
反应条件
1: anhydrous L-lysine monohydrochloride With di-tert-butyl dicarbonate; sodium hydrogencarbonate; copper(II) sulfate in water; acetone Metallation; 24 h; 2: benzyl chloroformate With 8-hydroxy-quinoline; N-hydroxy-3-aminocarbonylpropionamide; sodium carbonate in water; acetonitrile Substitution; 1 h;
参考文献
Organic Preparations and Procedures International, , vol. 31, # 4 p. 456 - 459
反应条件
1: lithium hydroxide hydrate / 4 °C 2: sodium hydroxide / ethanol / -20 °C View Scheme
参考文献
Bioconjugate Chemistry, , vol. 24, # 1 p. 26 - 35
