3-羟基-雌甾-1,3,5(10),6-四烯-17-酮合成路线 （共 19 条）
反应条件
in N,N-dimethyl-formamide T=30°C; 46 h; Corynebacterium simplex (ATCC 6946);
参考文献
Brosa; Ferrer; Malet; Amezaga
Journal of Organic Chemistry, 1989 , vol. 54, # 16 p. 3984 - 3985
反应条件
hydrogenchloride in methanol 2 h; Ambient temperature;
参考文献
Rao, Pemmaraju N.; Wang, Zhiqiang
Steroids, 1997 , vol. 62, # 6 p. 487 - 490
参考文献
Journal of the American Chemical Society, , vol. 72, p. 4531,4533
反应条件
toluene-4-sulfonic acid in methanol T=20°C; 5 h;
参考文献
Jing, Yu; Xu, Cheng-Gong; Ding, Kai; Lin, Jing-Rong; Jin, Rong-Hua; Tian, Wei-Sheng
Tetrahedron Letters, 2010 , vol. 51, # 24 p. 3242 - 3245
反应条件
phosphorus tribromide
参考文献
Journal of the American Chemical Society, , vol. 80, p. 5683,5686
反应条件
1: dibenzoyl peroxide; CCl4; N-bromo-succinimide 2: 2,4,6-trimethyl-pyridine 3: glass / 600 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 72, p. 4531,4533
反应条件
1: sodium methylate; methanol 2: PBr3 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 80, p. 5683,5686
反应条件
1: 2,4,6-trimethyl-pyridine 2: glass / 600 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 72, p. 4531,4533
反应条件
1: 96 percent / CrO3 in 96percent acetic acid / acetic acid / 1 h / Ambient temperature 2: 43 percent / 2,3,5,6-tetrachloro-1,4-benzoquinone / ethanol / 2 h / 50 °C 3: 74 percent / dimethylformamide / 46 h / 30 °C / Corynebacterium simplex (ATCC 6946) View Scheme
参考文献
Journal of Organic Chemistry, , vol. 54, # 16 p. 3984 - 3985
反应条件
1: 43 percent / 2,3,5,6-tetrachloro-1,4-benzoquinone / ethanol / 2 h / 50 °C 2: 74 percent / dimethylformamide / 46 h / 30 °C / Corynebacterium simplex (ATCC 6946) View Scheme
参考文献
Journal of Organic Chemistry, , vol. 54, # 16 p. 3984 - 3985
