3-(2-乙氧基苯基)丙酸合成路线 （共 7 条）
反应条件
potassium hydroxide in methanol T=60°C; 16 h; Inert atmosphere;
参考文献
Williams, John D.; Khan, Atiyya R.; Cardinale, Steven C.; Butler, Michelle M.; Bowlin, Terry L.; Peet, Norton P.
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 419 - 434
反应条件
1.1: hydrogen; palladium 10 on activated carbon / methanol / 48 h / 1810.07 Torr / |Inert atmosphere 2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C / |Inert atmosphere 2.2: 1 h / 0 - 20 °C / |Inert atmosphere 3.1: potassium hydroxide / methanol / 16 h / 60 °C / |Inert atmosphere View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 22, # 1 p. 419 - 434
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C / |Inert atmosphere 1.2: 1 h / 0 - 20 °C / |Inert atmosphere 2.1: potassium hydroxide / methanol / 16 h / 60 °C / |Inert atmosphere View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 22, # 1 p. 419 - 434
反应条件
1.1: potassium tert-butylate / tetrahydrofuran / 0.17 h / 0 °C / |Inert atmosphere 1.2: 2.08 h / |Inert atmosphere 2.1: hydrogen; palladium 10 on activated carbon / methanol / 48 h / 1810.07 Torr / |Inert atmosphere 3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C / |Inert atmosphere 3.2: 1 h / 0 - 20 °C / |Inert atmosphere 4.1: potassium hydroxide / methanol / 16 h / 60 °C / |Inert atmosphere View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 22, # 1 p. 419 - 434
反应条件
sodium ethanolate Verseifen des Produktes mit verd. Natronlauge;
参考文献
Justus Liebigs Annalen der Chemie, , vol. 216, p. 141
Justus Liebigs Annalen der Chemie, , vol. 226, p. 351
参考文献
Justus Liebigs Annalen der Chemie, , vol. 216, p. 141
Justus Liebigs Annalen der Chemie, , vol. 226, p. 351
参考文献
Justus Liebigs Annalen der Chemie, , vol. 216, p. 141
Justus Liebigs Annalen der Chemie, , vol. 226, p. 351
