3-(3,4-二羟基苯基)丙烯酸丁酯合成路线 （共 8 条）
反应条件
1: 1-carboxy-2-(3,4-dihydroxyphenyl)ethylene With thionyl chloride in 1,4-dioxane 1 h; Heating; 2: butan-1-ol in 1,4-dioxane Heating; Further stages.;
参考文献
Uwai, Koji; Osanai, Yuu; Imaizumi, Takuma; Kanno, Syu-ichi; Takeshita, Mitsuhiro; Ishikawa, Masaaki
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 16 p. 7795 - 7803
反应条件
piperidine; pyridine T=20°C; Knoevenagel-Doebner condensation; 24 h;
参考文献
Xia, Chun-Nian; Hu, Wei-Xiao
Journal of Chemical Research, 2005 , # 5 p. 332 - 334
反应条件
1: SOCl2 / dioxane / 3 h / 100 °C 2: dioxane / 6 h / 100 °C View Scheme
参考文献
Nagaoka, Takema; Banskota, Arjun H; Tezuka, Yasuhiro; Saiki, Ikuo; Kadota, Shigetoshi
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 10 p. 3351 - 3359
反应条件
in 1,4-dioxane T=100°C; 6 h;
参考文献
Nagaoka, Takema; Banskota, Arjun H; Tezuka, Yasuhiro; Saiki, Ikuo; Kadota, Shigetoshi
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 10 p. 3351 - 3359
反应条件
1: pyridine; piperidine / 3 h / 80 - 95 °C 2: sulfuric acid / 2 h / Heating 3: N,N-dimethylaniline; AlCl3 / CH2Cl2 / 2 h / 0 - 5 °C View Scheme
参考文献
Venkateswarlu, Somepalli; Ramachandra, Mareullapudi S.; Krishnaraju, Alluri V.; Trimurtulu, Golakoti; Subbaraju, Gottumukkala V.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 1 p. 252 - 257
反应条件
1: sulfuric acid / 2 h / Heating 2: N,N-dimethylaniline; AlCl3 / CH2Cl2 / 2 h / 0 - 5 °C View Scheme
参考文献
Venkateswarlu, Somepalli; Ramachandra, Mareullapudi S.; Krishnaraju, Alluri V.; Trimurtulu, Golakoti; Subbaraju, Gottumukkala V.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 1 p. 252 - 257
反应条件
1: potassium carbonate / acetone / 4 h / Heating 2: pyridine; piperidine / 3 h / 80 - 95 °C 3: sulfuric acid / 2 h / Heating 4: N,N-dimethylaniline; AlCl3 / CH2Cl2 / 2 h / 0 - 5 °C View Scheme
参考文献
Venkateswarlu, Somepalli; Ramachandra, Mareullapudi S.; Krishnaraju, Alluri V.; Trimurtulu, Golakoti; Subbaraju, Gottumukkala V.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 1 p. 252 - 257
反应条件
1: 35.8 percent / KOH / ethanol / 1 h / cooling 2: 67.8 percent / piperidine; pyridine / 24 h / 20 °C View Scheme
参考文献
Xia, Chun-Nian; Hu, Wei-Xiao
Journal of Chemical Research, 2005 , # 5 p. 332 - 334
