7-羟基-3,4-二氢-2H-1-萘酮合成路线 （共 21 条）
反应条件
aluminium trichloride in toluene Heating;
参考文献
Woo, L. W. Lawrence; Howarth, Nicola M.; Purohit, Atul; Hejaz, Hatem A. M.; Reed, Michael J.; Potter, Barry V. L.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 7 p. 1068 - 1083
参考文献
ZENECA LIMITED; ZENECA-PHARMA
Patent: EP695753 A1, 1996 ;
反应条件
aluminum tri-bromide; cyclohexane in various solvent(s) T=20°C; Hydrogenation; 28 h;
参考文献
Koltunov; Ostashevskaya; Repinskaya
Russian Journal of Organic Chemistry, 1998 , vol. 34, # 12 p. 1796 - 1797
反应条件
dihydrogen peroxide; hydrogen fluoride; SbF5 T=-40°C; 0.5 h; MechanismProduct distribution;
参考文献
Tetrahedron Letters, , vol. 24, # 30 p. 3095 - 3098
反应条件
1: 72 percent / NaHCO3, CF3CO3H, urea / acetonitrile / 1.42 h / 0 °C 2: 85 percent / pyridinium chlorochromate / CH2Cl2 / 3.2 h / 23 °C 3: toluene / 19 h / 80 °C 4: 1.) hydrochloric acid 2.)DBN / 1.) THF, 0 deg C, 30 min, 2.) 0 deg C, 1 h View Scheme
参考文献
Tetrahedron Letters, , vol. 22, p. 603 - 606
反应条件
1: toluene / 19 h / 80 °C 2: 1.) hydrochloric acid 2.)DBN / 1.) THF, 0 deg C, 30 min, 2.) 0 deg C, 1 h View Scheme
参考文献
Tetrahedron Letters, , vol. 22, p. 603 - 606
反应条件
1: 85 percent / pyridinium chlorochromate / CH2Cl2 / 3.2 h / 23 °C 2: toluene / 19 h / 80 °C 3: 1.) hydrochloric acid 2.)DBN / 1.) THF, 0 deg C, 30 min, 2.) 0 deg C, 1 h View Scheme
参考文献
Tetrahedron Letters, , vol. 22, p. 603 - 606
反应条件
1: With 2-[3,4-bis(picolinamide)phenyl]benzoic acid Mn(II) Esterification; 2: With iodosylbenzene in acetonitrile Oxidation; 3: With sodium hydroxide in methanol Hydrolysis;
参考文献
Angewandte Chemie (International Edition in English), , vol. 39, # 9 p. X1618-1621
反应条件
sodium acetate; dimethyl sulfoxide
参考文献
Monatshefte fuer Chemie, , vol. 95, p. 129 - 146
反应条件
potassium tert-butylate in dimethyl sulfoxide
参考文献
Warner-Lambert Company
Patent: US4767776 A1, 1988 ;
