反应条件
1: 89 percent / (o-MeC6H4)3P, Et3N / Pd(OAc)2 / acetonitrile / 3 h / Heating
2: LiAlH4 / diethyl ether
3: CH2Cl2
4: NaH / dimethylformamide
5: 100 percent / H2 / Pd/C / methanol
6: 82 percent / Fremy's salt / acetone; H2O
7: 1.) TFA, 2.) NaHCO3 / 1.) CH2Cl2, 2.) EtOH
8: CuCl2, Et3N, O2 / acetonitrile
9: NaOMe / methanol
View Scheme
参考文献
Aubart, Kelly Marshall; Heathcock, Clayton H.
Journal of Organic Chemistry, 1999 , vol. 64, # 1 p. 16 - 22