6-溴-2-氧代-2H-1-苯并吡喃-3-羧酸氯合成路线 （共 6 条）
反应条件
oxalyl dichloride; N,N-dimethyl-formamide in toluene T=60°C; 3 h; Product distribution / selectivity;
参考文献
NEUROSEARCH A/S
Patent: WO2008/74755 A2, 2008 ;
Location in patent: Page/Page column 33 ;
WO 2008/074755 A2
反应条件
1: aq. NaOH 2: SOCl2 / 3 h / 100 °C View Scheme
参考文献
Liu, Jinbing; Wu, Fengyan; Chen, Lingjuan; Zhao, Liangzhong; Zhao, Zibing; Wang, Min; Lei, Sulan
Food Chemistry, 2012 , vol. 135, # 4 p. 2872 - 2878
反应条件
1: piperidine / ethanol / 24 h / Heating 2: aq. NaOH 3: SOCl2 / 3 h / 100 °C View Scheme
参考文献
Chimenti, Franco; Secci, Daniela; Bolasco, Adriana; Chimenti, Paola; Granese, Arianna; Befani, Olivia; Turini, Paola; Alcaro, Stefano; Ortuso, Francesco
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 14 p. 3697 - 3703
反应条件
1: chloroform; bromine 2: piperidine 3: aq. NaOH solution 4: thionyl chloride View Scheme
参考文献
Clinton; Laskowski
Journal of the American Chemical Society, 1949 , vol. 71, p. 3602,3604
反应条件
1: aq. NaOH 2: 98 percent / SOCl2 View Scheme
参考文献
Chimenti, Franco; Secci, Daniela; Bolasco, Adriana; Chimenti, Paola; Granese, Arianna; Befani, Olivia; Turini, Paola; Alcaro, Stefano; Ortuso, Francesco
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 14 p. 3697 - 3703
反应条件
1: aq. NaOH 2: 98 percent / SOCl2 View Scheme
参考文献
Chimenti, Franco; Secci, Daniela; Bolasco, Adriana; Chimenti, Paola; Granese, Arianna; Befani, Olivia; Turini, Paola; Alcaro, Stefano; Ortuso, Francesco
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 14 p. 3697 - 3703
