2,4-二甲基-3-吡咯羧酸乙酯合成路线 （共 45 条）
反应条件
chloroform; trichlorophosphate
参考文献
Treibs; Hintermeier
Justus Liebigs Annalen der Chemie, 1957 , vol. 605, p. 35,42
反应条件
1.1: trichlorophosphate / 2 - 3 h / 0 - 50 °C 1.2: 25 - 30 °C / pH 12 - 13 2.1: potassium hydroxide; water / methanol / 4 - 6 h / 60 - 70 °C View Scheme
参考文献
Elsinghorst, Paul W.; Guetschow, Michael
Journal of Labelled Compounds and Radiopharmaceuticals, 2009 , vol. 52, # 9 p. 360 - 365
反应条件
water; potassium hydroxide in methanol Reflux;
参考文献
Komatsu, Toru; Urano, Yasuteru; Fujikawa, Yuuta; Kobayashi, Tomonori; Kojima, Hirotatsu; Terai, Takuya; Hanaoka, Kenjiro; Nagano, Tetsuo
Chemical Communications, 2009 , # 45 p. 7015 - 7017
反应条件
1: diethyl ether; hydrogen chloride / Spaltung des entstandenen Imid-Hydrochlorids mit Wasser
2: concentrated nitric acid
View Scheme
参考文献
Treibs; Kolm
Justus Liebigs Annalen der Chemie, 1958 , vol. 614, p. 176,195
参考文献
Canadian Patents and Development Limited
Patent: US4070366 A1, 1978 ;
反应条件
ethanol; acetic acid
参考文献
Fischer,H.; Bartholomaeus
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1913 , vol. 87, p. 261
反应条件
1: acetic acid
2: ethanolic KOH
View Scheme
参考文献
Kleinspehn; Corwin
Journal of the American Chemical Society, 1954 , vol. 76, p. 5641,5645
参考文献
Treibs; Reitsam
Justus Liebigs Annalen der Chemie, 1958 , vol. 611, p. 205,222
参考文献
Treibs; Reitsam
Justus Liebigs Annalen der Chemie, 1958 , vol. 611, p. 205,222
参考文献
Treibs; Reitsam
Justus Liebigs Annalen der Chemie, 1958 , vol. 611, p. 205,222
