4-三甲基甲硅烷基苯甲醛合成路线 （共 16 条）
反应条件
1: 4-(trimethylsilyl)bromobenzene With n-butyllithium in tetrahydrofuran; hexane; N,N-dimethyl-formamide T=-78 - -70°C; 0.25 h; 2: N,N-dimethyl-formamide in tetrahydrofuran; hexane T=-78 - -68°C; 0.25 h;
参考文献
Conte, Aurelia; Kuehne, Holger; Luebbers, Thomas; Mattei, Patrizio; Maugeais, Cyrille; Mueller, Werner; Pflieger, Philippe
Patent: US2007/185058 A1, 2007 ;
Location in patent: Page/Page column 9 ;
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=-78 - -70°C; 0.25 h; 2: With N,N-dimethyl-formamide in tetrahydrofuran; hexane T=-78 - -68°C; 0.25 h;
参考文献
Conte, Aurelia; Kuehne, Holger; Luebbers, Thomas; Mattei, Patrizio; Maugeais, Cyrille; Mueller, Werner; Pflieger, Philippe
Patent: US2007/185182 A1, 2007 ;
Location in patent: Page/Page column 12 ;
反应条件
sodium hydroxide; diphenyl-(o-hydroxyphenyl)-phosphine; PdCl(π-C3H5)2 in tetrahydrofuran T=100°C; Substitution; Silylation; 24 h;
参考文献
Shirakawa; Kurahashi; Yoshida; Hiyama
Chemical Communications, 2000 , # 19 p. 1895 - 1896
反应条件
1: With diisobutylaluminium hydride in toluene T=45°C; 2 h; 2: With water; ammonium chloride in toluene T=20°C; 1 h;
参考文献
EP1640360 A1, ;
Page/Page column 85 ;
参考文献
Gmelin Handbook: Si: MVol.C, 22, page 68 - 71
反应条件
1: dibenzoyl peroxide; N-bromo-succinimide 2: 2-nitro-propane; ethanolic sodium ethylate View Scheme
参考文献
Journal of the American Chemical Society, , vol. 79, p. 6540
反应条件
2-Nitropropane; sodium ethanolate
参考文献
Journal of the American Chemical Society, , vol. 79, p. 6540
参考文献
Journal of the American Chemical Society, , vol. 79, p. 6540
反应条件
diisobutylaluminium hydride in hexane; dichloromethane 4.5 h; Ambient temperature; Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 64, # 6 p. 2057 - 2065
反应条件
1.1: n-butyllithium / diethyl ether; hexane / 0.5 h / -78 °C 1.2: 88 percent / diethyl ether; hexane / 1.5 h / -78 - 20 °C 2.1: n-butyllithium / diethyl ether; hexane / 2 h / 0 - 20 °C 2.2: diethyl ether; hexane 2.3: 75 percent / hydrochloric acid / H2O; diethyl ether; hexane View Scheme
参考文献
Tetrahedron, , vol. 59, # 20 p. 3593 - 3601
