4-甲基 哌嗪-1,4-二羧酸-1-叔丁酯合成路线 (共 3 条)
反应条件
1: piperazine-1-carboxylic acid tert-butyl ester With 4-(N,N-dimethlyamino)pyridine; N-ethyl-N,N-diisopropylamine in dichloromethane 2: methyl chloroformate
参考文献
Zulli, Allison L.; Aimone, Lisa D.; Mathiasen, Joanne R.; Gruner, John A.; Raddatz, Rita; Bacon, Edward R.; Hudkins, Robert L.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 8 p. 2807 - 2810
反应条件
trifluoroacetic acid in dichloromethane
参考文献
Zulli, Allison L.; Aimone, Lisa D.; Mathiasen, Joanne R.; Gruner, John A.; Raddatz, Rita; Bacon, Edward R.; Hudkins, Robert L.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 8 p. 2807 - 2810
反应条件
L-Selectridereg; in tetrahydrofuran T=20°C; 48 h;
参考文献
Tetrahedron Letters, , vol. 39, # 49 p. 8933 - 8934