N-苄氧羰基-L-苯丙氨腈合成路线 （共 5 条）
反应条件
2,4,6-trichloro-1,3,5-triazine in N,N-dimethyl-formamide T=0 - 20°C;
参考文献
SEATTLE GENETICS, INC.
Patent: WO2007/8848 A2, 2007 ;
Location in patent: Page/Page column 147 ;
反应条件
ammonium hydroxide; iodine in tetrahydrofuran T=25°C;
参考文献
Shie, Jiun-Jie; Fang, Jim-Min
Journal of Organic Chemistry, 2007 , vol. 72, # 8 p. 3141 - 3144
反应条件
1: NaHCO3 / H2O 2: ethyl chloroformate; aq. ammonia; triethylamine / tetrahydrofuran / 0.5 h / 0 °C 3: 7.7 g / phosphorus oxychloride; pyridine / 0 - 20 °C View Scheme
参考文献
Organic Letters, , vol. 9, # 13 p. 2521 - 2524
反应条件
1: ethyl chloroformate; aq. ammonia; triethylamine / tetrahydrofuran / 0.5 h / 0 °C 2: 7.7 g / phosphorus oxychloride; pyridine / 0 - 20 °C View Scheme
参考文献
Organic Letters, , vol. 9, # 13 p. 2521 - 2524
反应条件
1: NaHCO3 / H2O 2: ethyl chloroformate; aq. ammonia; triethylamine / tetrahydrofuran / 0.5 h / 0 °C 3: 7.7 g / phosphorus oxychloride; pyridine / 0 - 20 °C View Scheme
参考文献
Organic Letters, , vol. 9, # 13 p. 2521 - 2524
