3-甲基-2-苯并恶唑酮合成路线 （共 63 条）
反应条件
1: 80 percent / polyphosphoric acid / 4.5 h / 120 °C 2: 85 percent / NaOH View Scheme
参考文献
Moussavi, Ziaeddine; Lesieur, Daniel; Lespagnol, Charles; Sauzieres, Jacques; Olivier, Philippe
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 55 - 60
反应条件
1: 70 percent / polyphosphoric acid 2: 60 percent / NaOH 3: 80 percent / C2H5ONa / dimethylsulfoxide / 3 h / Ambient temperature 4: 70 percent / HCl gas / ethanol / 2 h / Ambient temperature View Scheme
参考文献
Moussavi, Ziaeddine; Lesieur, Daniel; Lespagnol, Charles; Sauzieres, Jacques; Olivier, Philippe
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 55 - 60
反应条件
1: 70 percent / polyphosphoric acid 2: 85 percent / NaOH 3: 75 percent / C2H5ONa / dimethylsulfoxide / 3 h / Ambient temperature View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 24, p. 55 - 60
反应条件
1: 80 percent / polyphosphoric acid / 1.5 h / 100 °C 2: 70 percent / NaOH View Scheme
参考文献
Moussavi; Depreux; Lesieur; Cotelle; Sauzieres; Plancke; Fruchart
Farmaco, 1991 , vol. 46, # 2 p. 339 - 355
反应条件
1: 70 percent / polyphosphoric acid 2: 60 percent / NaOH 3: 75 percent / C2H5ONa / dimethylsulfoxide / 3 h / Ambient temperature 4: 65 percent / HCl gas / ethanol / 2 h / Ambient temperature View Scheme
参考文献
Moussavi, Ziaeddine; Lesieur, Daniel; Lespagnol, Charles; Sauzieres, Jacques; Olivier, Philippe
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 55 - 60
反应条件
1: 70 percent / polyphosphoric acid 2: 60 percent / NaOH 3: 75 percent / C2H5ONa / dimethylsulfoxide / 3 h / Ambient temperature View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 24, p. 55 - 60
参考文献
Moussavi, Ziaeddine; Lesieur, Daniel; Lespagnol, Charles; Sauzieres, Jacques; Olivier, Philippe
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 55 - 60
反应条件
aluminium trichloride; lithium perchlorate in nitromethane T=50 - 55°C; Friedel-Crafts acylation; 12 h;
参考文献
Poupaert, Jacques H.; Depreux, Patrick; McCurdy, Christopher R.
Monatshefte fur Chemie, 2003 , vol. 134, # 6 p. 823 - 830
反应条件
1: 80 percent / polyphosphoric acid / 1.5 h / 100 °C 2: 70 percent / NaOH 3: 75 percent / C2H5ONa / dimethylsulfoxide / 3 h / Ambient temperature View Scheme
参考文献
Moussavi; Depreux; Lesieur; Cotelle; Sauzieres; Plancke; Fruchart
Farmaco, 1991 , vol. 46, # 2 p. 339 - 355
反应条件
1: 85 percent / polyphosphoric acid / 0.75 h / 165 °C 2: 97 percent / HBr / acetone / 1 h / Ambient temperature 3: 78 percent / triethylamine / benzene / 15 h / Heating View Scheme
参考文献
Moussavi; Bonte; Lesieur; Leinot; Lamar; Tisne-Versailles
Farmaco (Societa chimica italiana : 1989), 1989 , vol. 44, # 1 p. 77 - 88
