3-甲基-2-苯并恶唑酮合成路线 （共 63 条）
反应条件
Lawesson's reagent in xylene 3 h; Heating;
参考文献
Shridhar, D. R.; Jogibhukta, M.; Shanthan Rao, P.; Handa, Vijay K.
Synthesis, 1983 , # 11 p. 936 - 937
反应条件
1: 80 percent / polyphosphoric acid / 1.5 h / 100 °C 2: 70 percent / aq. sodium hydroxide / Heating 3: 85 percent / sodium hydrogencarbonate / butan-2-one; H2O / 8 h / 90 °C 4: 85 percent / acetic anhydride / 3 h / 90 - 100 °C 5: 87 percent / triethylamine / 72 h View Scheme
参考文献
Moussavi; Depreux; Lesieur; Cotelle; Sauzieres; Plancke; Fruchart
Farmaco, 1991 , vol. 46, # 2 p. 339 - 355
反应条件
1: 70 percent / polyphosphoric acid 2: 60 percent / NaOH 3: 75 percent / C2H5ONa / dimethylsulfoxide / 3 h / Ambient temperature View Scheme
参考文献
Moussavi, Ziaeddine; Lesieur, Daniel; Lespagnol, Charles; Sauzieres, Jacques; Olivier, Philippe
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 55 - 60
反应条件
1: 80 percent / polyphosphoric acid / 1.5 h / 100 °C 2: 70 percent / NaOH 3: 85 percent / C2H5ONa / dimethylsulfoxide / 3 h / Ambient temperature View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 24, p. 55 - 60
反应条件
1: 70 percent / polyphosphoric acid 2: 60 percent / NaOH 3: 75 percent / C2H5ONa / dimethylsulfoxide / 3 h / Ambient temperature 4: 65 percent / HCl gas / ethanol / 2 h / Ambient temperature View Scheme
参考文献
Moussavi, Ziaeddine; Lesieur, Daniel; Lespagnol, Charles; Sauzieres, Jacques; Olivier, Philippe
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 55 - 60
反应条件
1: 70 percent / polyphosphoric acid 2: 60 percent / NaOH 3: 80 percent / C2H5ONa / dimethylsulfoxide / 3 h / Ambient temperature View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 24, p. 55 - 60
反应条件
1: 80 percent / polyphosphoric acid / 4.5 h / 120 °C 2: 85 percent / NaOH 3: 60 percent / C2H5ONa / dimethylsulfoxide / 3 h / Ambient temperature View Scheme
参考文献
Moussavi, Ziaeddine; Lesieur, Daniel; Lespagnol, Charles; Sauzieres, Jacques; Olivier, Philippe
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 55 - 60
反应条件
1: 80 percent / polyphosphoric acid / 4.5 h / 120 °C 2: 85 percent / NaOH 3: 70 percent / C2H5ONa / dimethylsulfoxide / 3 h / Ambient temperature View Scheme
参考文献
Moussavi, Ziaeddine; Lesieur, Daniel; Lespagnol, Charles; Sauzieres, Jacques; Olivier, Philippe
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 55 - 60
反应条件
1: 80 percent / polyphosphoric acid / 1.5 h / 100 °C 2: 70 percent / NaOH 3: 75 percent / C2H5ONa / dimethylsulfoxide / 3 h / Ambient temperature View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 24, p. 55 - 60
反应条件
1: 80 percent / polyphosphoric acid / 1.5 h / 100 °C 2: 70 percent / aq. sodium hydroxide / Heating 3: 75 percent / sodium hydrogencarbonate / butan-2-one; H2O / 8 h / 90 °C 4: 80 percent / acetic anhydride / 3 h / 90 - 100 °C View Scheme
参考文献
Moussavi; Depreux; Lesieur; Cotelle; Sauzieres; Plancke; Fruchart
Farmaco, 1991 , vol. 46, # 2 p. 339 - 355
