反应条件
Stage #1: <a href="#" onclick="return RXDsubstances(event, this, '1719096', constants.ctx, '0')">propenyl bromide</a> <b>With</b> <a href="#" onclick="return RXDsubstances(event, this, '1209227', constants.ctx, '0')">n-butyllithium</a> <b>in</b> <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>; <a href="#" onclick="return RXDsubstances(event, this, '1730733', constants.ctx, '0')">hexane</a> <br />T=-78°C; Elimination; metallation; 2 h; <br />Stage #2: <a href="#" onclick="return RXDsubstances(event, this, '1911173', constants.ctx, '0')">di-<i>tert</i>-butyl dicarbonate</a> <b>in</b> <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />T=4°C; Carboxylation; 10 h; Further stages.; <br />
参考文献
Otaka, Akira; Mitsuyama, Etsuko; Kinoshita, Takayoshi; Tamamura, Hirokazu; Fujii, Nobutaka Journal of Organic Chemistry, 2000 , vol. 65, # 16 p. 4888 - 4899
