[(1S,2R)-2-羟基-2,3-二氢-1H-茚-1-基]氨基甲酸叔丁酯合成路线 （共 5 条）
反应条件
methanol; sodium methylate in dichloromethane T=0°C; 2.16667 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2005/32490 A2, 2005 ;
Location in patent: Page/Page column 64-65 ;
WO 2005/032490 A2
反应条件
sodium carbonate in tetrahydrofuran; water T=0 - 20°C; 3 h; Inert atmosphere;
参考文献
Gao, Yaojun; Ren, Qiao; Wu, Hao; Li, Maoguo; Wang, Jian
Chemical Communications, 2010 , vol. 46, # 48 p. 9232 - 9234
Title/Abstract Full Text View citing articles Show Details
Ren, Qiao; Gao, Yaojun; Wang, Jian
Chemistry - A European Journal, 2010 , vol. 16, # 46 p. 13594 - 13598
反应条件
in dichloromethane T=20°C; 0.0833333 h;
参考文献
Shimizu, Mamoru; Sodeoka, Mikiko
Heterocycles, 2008 , vol. 76, # 2 p. 1301 - 1312
反应条件
chiral N-4'-pyridinyl-α-methylproline derivative in chloroform T=20°C; 16 h; Title compound not separated from byproducts;
参考文献
Pelotier, Beatrice; Priem, Ghislaine; Macdonald, Simon J.F.; Anson, Mike S.; Upton, Richard J.; Campbell, Ian B.
Tetrahedron Letters, 2005 , vol. 46, # 52 p. 9005 - 9007
反应条件
1: DEAD; PPh3
2: NaOMe / methanol
View Scheme
参考文献
Qiao, Jennifer X.; Wang, Tammy C.; Wang, Gren Z.; Cheney, Daniel L.; He, Kan; Rendina, Alan R.; Xin, Baomin; Luettgen, Joseph M.; Knabb, Robert M.; Wexler, Ruth R.; Lam, Patrick Y.S.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 18 p. 5041 - 5048
