1-环己基丙-2-烯-1-酮合成路线 （共 21 条）
反应条件
chromium(VI) oxide; alpha,alpha-dimethylbenzyl hydroperoxide in dichloromethane
41 h; Ambient temperature; Yield givenYields of byproduct given. Title compound not separated from byproducts;
参考文献
Riahi, Abdelkhalek; Henin, Francoise; Muzart, Jacques
Tetrahedron Letters, 1999 , vol. 40, # 12 p. 2303 - 2306
反应条件
phosphorus pentoxide in toluene
Heating;
参考文献
Kugatova-Shemyakina,G.P.; Vesa,V.S.
Doklady Chemistry, 1961 , vol. 140, p. 908 - 911
Doklady Akademii Nauk SSSR, 1961 , vol. 140, # 2 p. 377 - 380
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Kugatova-Shemyakina,G.P.; Vesa,V.S.
J. Gen. Chem. USSR (Engl. Transl.), 1963 , vol. 33, # 12 p. 3875 - 3883,3813 - 3820
反应条件
in diethyl ether
T=220 - 270°C;
参考文献
Ganter,C.; Moser,J.-F.
Helvetica Chimica Acta, 1971 , vol. 54, p. 2228 - 2251
反应条件
1: 77 percent / LDA / tetrahydrofuran / -60 °C
2: 93 percent / t-BuOK / benzene; 2-methyl-propan-2-ol / Ambient temperature
3: 94 percent / NaBH4, diphenyl diselenide / ethanol / 0 °C
4: 74 percent / 10percent aq. KOH / benzene / 3 h / Ambient temperature
View Scheme
参考文献
Satoh, Tsuyoshi; Kumagawa, Takumi; Sugimoto, Atsushi; Yamakawa, Koji
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 1 p. 301 - 310
反应条件
N-methylaniline; trifluoroacetic acid in tetrahydrofuran
5 h; Heating;
参考文献
Pavlyuchenko, A. I.; Purvanetskas, G. V.; Daukshas, V. K.; Smirnova, N. I.; Korotkova, N. I.; at al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 5 p. 515 - 518
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , vol. 20, # 5 p. 643 - 647
反应条件
1: dioxane / 12 h / Heating
2: 79.5 percent / glacial CH3COOH, conc. H2SO4 / 3 h / Ambient temperature
View Scheme
参考文献
Fatmi, Aqeel A.; Vaidya, Niteen A.; Iturrian, W. B.; Blanton, C. DeWitt
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 772 - 778
反应条件
1: dioxane / 12 h / Heating
2: 79.5 percent / glacial CH3COOH, conc. H2SO4 / 3 h / Ambient temperature
3: 91.6 percent / HCOOH / 4 h / 170 - 180 °C
View Scheme
参考文献
Fatmi, Aqeel A.; Vaidya, Niteen A.; Iturrian, W. B.; Blanton, C. DeWitt
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 772 - 778
反应条件
1: dioxane / 12 h / Heating
2: 79.5 percent / glacial CH3COOH, conc. H2SO4 / 3 h / Ambient temperature
3: 98.7 percent / 3 h / 125 - 130 °C
4: 82 percent / CH3COONH4 / dimethylsulfoxide / a) RT, 24 h, b) 75 deg C to 80 deg C, 2 h
View Scheme
参考文献
Fatmi, Aqeel A.; Vaidya, Niteen A.; Iturrian, W. B.; Blanton, C. DeWitt
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 772 - 778
反应条件
1: 75 percent / 80 h / 20 °C
2: 46 percent / NH2OH.HCl / ethanol / 2 h / Heating
View Scheme
参考文献
Pavlyuchenko, A. I.; Purvanetskas, G. V.; Daukshas, V. K.; Smirnova, N. I.; Korotkova, N. I.; at al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 5 p. 515 - 518
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , vol. 20, # 5 p. 643 - 647
反应条件
diethylzinc; copper(II) bis(trifluoromethanesulfonate) in diethyl ether
82 h;
参考文献
Fujii, Kanami; Misaki, Tomonori; Sugimura, Takashi
Chemistry Letters, 2014 , vol. 43, # 5 p. 634 - 636
