6,6-二甲基-5-亚甲基-1,3-环戊二烯合成路线 （共 71 条）
反应条件
1: 72 percent / acetone / 4 h / -60 - 20 °C 2: 56 percent / p-toluenesulfonic acid monohydrate / CDCl3 / 1 h / Heating View Scheme
参考文献
Howard, Michael H.; Alexander; Marshall, William J.; Roe, D. Christopher; Zheng
Journal of Organic Chemistry, 2003 , vol. 68, # 1 p. 120 - 129
反应条件
in Petroleum ether T=27°C; 168 h;
参考文献
Journal of Organic Chemistry, , vol. 46, # 11 p. 2306 - 2310
反应条件
in Petroleum ether T=27°C; 168 h; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 46, # 11 p. 2306 - 2310
反应条件
in neat (no solvent) (Ar); using Schlenk techniques; heating of 0.8 mmol of 6,6-dimethylfulvene with 0.2 mmol of Re2(CO)10 at 155°C for 2 h; filtration on silica gel (petroleum ether-CH2Cl2, 95:5), as oil;
参考文献
Le Bideau; Henique; Pigeon; Joerger; Top; Jaouen
Journal of Organometallic Chemistry, 2003 , vol. 668, # 1-2 p. 140 - 144
反应条件
lithium diisopropyl amide; triphenylphosphine; bis(dibenzylideneacetone)-palladium(0) 1) THF, -78 deg C 2) THF, 0 deg C, 25 min; Yield given. Multistep reaction;
参考文献
Soederberg, Bjoern C.; Austin, Lucinda R.; Davis, Carol A.; Nystroem, Jan-Erik; Vagberg, Jan O.
Tetrahedron, 1994 , vol. 50, # 1 p. 61 - 76
反应条件
1: 83 percent / LiAlH4 / diethyl ether / 1 h / Ambient temperature 2: 75 percent / KOH / ethanol / 12 h / Ambient temperature 3: 50 percent / Et3N / hexane / 13 h / Ambient temperature 4: 63 percent / aq. NaOH / acetic acid / 10 h / Heating 5: 43 percent / NaN3, conc. H2SO4 / 3 h / 50 °C View Scheme
参考文献
Imafuku, Kimiaki; Arai, Kiyomi
Synthesis, 1989 , # 7 p. 501 - 505
反应条件
in tetrahydrofuran reduction of fulvene with Na2C10H8 in THF (dry, O2 free), addn. of TiCl3*THF, Schlenk technique, Ar;
参考文献
Schwemlein, Heinz; Brintzinger, Hans H.
Journal of Organometallic Chemistry, 1983 , vol. 254, # 1 p. 69 - 74
反应条件
in toluene under Ar, 2 equiv. of nBuLi in hexane was added to toluene soln. of TiCl4 at -78 °C, 30 min, 2 equiv. of fulvene-compd. was adde, armign to room temp. and to 65 °C;
参考文献
Eisch, John J.; Owuor, Fredrick A.; Shi, Xian
Polyhedron, 2005 , vol. 24, # 11 p. 1325 - 1339
反应条件
1: 83 percent / LiAlH4 / diethyl ether / 1 h / Ambient temperature 2: 75 percent / KOH / ethanol / 12 h / Ambient temperature View Scheme
参考文献
Imafuku, Kimiaki; Arai, Kiyomi
Synthesis, 1989 , # 7 p. 501 - 505
反应条件
in 2-methyl cyclohexane (N2); refluxed for 180 min; solvent removed, chromd. (Al2O3, pentane/ether) at 253 K, solvent removed, distd. (vac.); elem. anal.;
参考文献
Kreiter, Cornelius G.; Lipps, Wolfgang
Journal of Organometallic Chemistry, 1983 , vol. 253, # 3 p. 339 - 348
