3-苯基-3-(2,2,2-三氟乙酰氨基)丙酸合成路线 （共 8 条）
反应条件
0.5 h; Ambient temperature;
参考文献
Luan, Feng; Cordeiro, M. Natalia D.S.; Alonso, Nerea; Garcia-Mera, Xerardo; Caamano, Olga; Romero-Duran, Francisco J.; Yanez, Matilde; Gonzalez-Diaz, Humberto
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 7 p. 1870 - 1879
参考文献
Wu, Dongpei; Pontillo, Joseph; Ching, Brett; Hudson, Sarah; Gao, Yinghong; Fleck, Beth A.; Gogas, Kathleen; Wade, Warren S.
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 14 p. 4224 - 4227
反应条件
1: 65 percent / AcONH4 / ethanol / 6 h / Heating 2: 85 percent / 0.5 h / Ambient temperature View Scheme
参考文献
Rault, Sylvain; Dallemagne, Patrick; Robba, Max
Bulletin de la Societe Chimique de France, 1987 , # 6 p. 1079 - 1083
反应条件
in acetonitrile 21 h; Heating;
参考文献
Mattingly; Miller
Journal of Organic Chemistry, 1981 , vol. 46, # 8 p. 1557 - 1564
反应条件
1: oxalyl chloride / CH2Cl2 2: pyridine / CH2Cl2 3: Heating 4: aq. NaOH / tetrahydrofuran View Scheme
参考文献
Leflemme, Nicolas; Dallemagne, Patrick; Rault, Sylvain
Tetrahedron Letters, 2001 , vol. 42, # 51 p. 8997 - 8999
反应条件
1: 1.) triethylamine, ethyl chloroformate, 2.) sodium azide / 1.) acetone, 0-5 deg C,, 30 min, 2.) acetone, H2O, 1 h 2: H2O / CHCl3 / 0.5 h / Heating View Scheme
参考文献
Rault, Sylvain; Tembo, Olivier N.; Dallemagne, Patrick; Robba, Max
Heterocycles, 1991 , vol. 32, # 7 p. 1301 - 1305
反应条件
1: thionyl chloride / benzene / 0.5 h / Heating 2: 77 percent / aluminium chloride / CS2 / 6 h / Heating View Scheme
参考文献
Rault, S.; Pilo, J. C.; Dallemagne, P.; Foloppe, M. P.; Robba, M.
Bulletin de la Societe Chimique de France, 1990 , # 2 p. 316 - 323
反应条件
1: thionyl chloride / benzene / 0.5 h / Heating 2: 77 percent / aluminium chloride / CS2 / 6 h / Heating 3: sodium hydroxide / H2O / 0.5 h View Scheme
参考文献
Rault, Sylvain; Dallemagne, Patrick; Robba, Max
Bulletin de la Societe Chimique de France, 1987 , # 6 p. 1079 - 1083
