4-(4-乙酰氨基苯基)-2-氨基噻唑合成路线 （共 8 条）
反应条件
iron; ammonium chloride in acetone T=4°C; 0.25 h;
参考文献
FUJIFILM Corporation; TATEISHI, Keiichi; FUJIE, Yoshihiko; TANAKA, Shigeaki
Patent: EP2604656 A1, 2013 ;
Location in patent: Paragraph 0317; 0319 ;
反应条件
1: AlCl3 / CH2Cl2 / 1.) reflux, 7 h, 2.) RT, overnight 2: ethanol / 1 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 26, # 8 p. 1158 - 1163
反应条件
1.1: water / 5 h / 70 °C 1.2: 3 h / 20 °C 2.1: iron; ammonium chloride / water; isopropyl alcohol / 1 h / |Reflux 3.1: iron; ammonium chloride / acetone / 0.25 h / 4 °C View Scheme
反应条件
1: iron; ammonium chloride / water; isopropyl alcohol / 1 h / |Reflux 2: iron; ammonium chloride / acetone / 0.25 h / 4 °C View Scheme
反应条件
iodine 8 h; Heating;
参考文献
Sutariya, Bhavin; Raziya; Mohan; Rao, S.V. Sambasiva
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2007 , vol. 46, # 5 p. 884 - 887
反应条件
1: Br2 / acetic acid 2: Heating View Scheme
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. 311, p. 168 - 170
反应条件
in ethanol 1 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 26, # 8 p. 1158 - 1163
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. 311, p. 168 - 170
