5-((三甲基甲硅烷基)乙炔)嘧啶合成路线 （共 5 条）
反应条件
triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide T=80°C;
参考文献
Eckert, Thomas; Ipaktschi, Junes
Monatshefte fur Chemie, 1998 , vol. 129, # 10 p. 1035 - 1048
反应条件
bis-triphenylphosphine-palladium(II) chloride 12 h; Heating;
参考文献
Gelman, Dmitri; Tsvelikhovsky, Dmitry; Molander, Gary A.; Blum, Jochanan
Journal of Organic Chemistry, 2002 , vol. 67, # 18 p. 6287 - 6290
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine in acetonitrile T=120°C; Sonogashira Cross-Coupling; 0.75 h; Microwave irradiation;
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 7 p. 3033 - 3047
反应条件
tetrabutyl ammonium fluoride in dichloromethane T=25°C; 0.0833333 h;
参考文献
Eckert, Thomas; Ipaktschi, Junes
Monatshefte fur Chemie, 1998 , vol. 129, # 10 p. 1035 - 1048
反应条件
in methanol T=20°C; 2 h;
参考文献
Hebeisen, Paul; Roever, Stephan
Patent: US2008/70931 A1, 2008 ;
Location in patent: Page/Page column 12 ;
US 20080070931 A1
